Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.
Physical Medicine and Rehabilitation Research - Copenhagen (PMR-C), Clinical Research Center, Amager-Hvidovre Hospital, University of Copenhagen, Copenhagen, Denmark.
Scand J Med Sci Sports. 2020 May;30(5):837-848. doi: 10.1111/sms.13632. Epub 2020 Feb 21.
Heavy-load strength training (HLT) is generally considered the Gold Standard exercise modality for inducing gains in skeletal muscle strength. However, use of heavy external exercise loads may be contraindicative in frail individuals. Low-load resistance exercise combined with partial blood-flow restriction (LL-BFR exercise) may offer an effective alternative for increasing mechanical muscle strength and size. The aim of this study was to compare the effect of LL-BFR training to HLT on maximal muscle strength gains. Prospero registration-id (CRD42014013382).
A systematic search in six healthcare science databases and reference lists was conducted. Data selected for primary analysis consisted of post-intervention changes in maximal muscle strength. A random-effects meta-analysis with standardized mean differences (SMD) was used.
Of 1413 papers identified through systematic search routines, sixteen papers fulfilled the inclusion criteria, totalling 153 participants completing HLT and 157 completing LL-BFR training. The magnitude of training-induced gains in maximal muscle strength did not differ between LL-BFR training and HLT (SMD of -0.17 (95% CI: -0.40; 0.05)). Low between-study heterogeneity was noted (I = 0.0%, Chi P = 9.65).
Low-load blood-flow-restricted training appears equally effective of producing gains in maximal voluntary muscle strength compared to HLT in 20- to 80-year-old healthy and habitually active adults.
大负荷强度训练（HLT）通常被认为是增强骨骼肌力量的黄金标准运动方式。然而，在虚弱个体中，使用大外部运动负荷可能是禁忌的。低负荷阻力训练结合部分血流限制（LL-BFR 训练）可能是增加机械肌肉力量和大小的有效替代方法。本研究旨在比较 LL-BFR 训练与 HLT 对最大肌肉力量增长的影响。Prospéro 注册号（CRD42014013382）。
对六个医疗保健科学数据库和参考文献列表进行了系统搜索。主要分析中选择的数据包括干预后最大肌肉力量的变化。使用标准化均数差（SMD）进行随机效应荟萃分析。
通过系统搜索程序共确定了 1413 篇论文，其中 16 篇符合纳入标准，共有 153 名参与者完成了 HLT，157 名参与者完成了 LL-BFR 训练。最大肌肉力量的训练诱导增益在 LL-BFR 训练和 HLT 之间没有差异（SMD 为-0.17（95%CI：-0.40；0.05））。研究之间的异质性较低（I = 0.0%，Chi P = 9.65）。
与 HLT 相比，低负荷血流限制训练在 20 至 80 岁健康且习惯性活跃的成年人中产生最大自主肌肉力量的增益似乎同样有效。
