Sacco W J, Jameson J W, Copes W S, Lawnick M M, Keast S L, Champion H R
Washington Hospital Center, Washington, D.C.
Comput Biol Med. 1988;18(6):419-29. doi: 10.1016/0010-4825(88)90059-5.
Presented is a new seven-dimensional injury severity profile. The profile includes three physiologic assessments and four variables which express the number, location, and severity of a patient's injuries in terms of 'Abbreviated injury scale' values. The physiologic assessments are coded values for the 'Glasgow coma scale', systolic blood pressure, and respiratory rate. Also presented are survival-death predictive values of a cluster model based on survival rates of clusters of profiles of 2569 blunt-injured and penetrating-injured patients. The cluster model has a relative information gain (R) of 0.90. R is a measure of predictive value relative to an infallible predictor. It varies from 0 to 1, the higher the value the better the predictive value. The model had 26 false negatives (deaths predicted to survive) and 35 false positives (survivors predicted to die) giving rise to a false negative rate of 9.3%, a false positive rate of 1.4% and a misclassification rate of 2.4%. The R value and false negative rate are particularly noteworthy, the R value being higher than, and the false negative rate much lower than typical values of 30-40% achieved by TRISS (a combination index based on trauma score, injury severity score and patient age). Also noteworthy is that the clustering was independent of survival/death outcome information and that the good results were achieved even though patient age has not yet been incorporated into the model.
本文介绍了一种新的七维损伤严重程度概况。该概况包括三项生理评估和四个变量,这些变量根据“简明损伤定级标准”的值来表示患者损伤的数量、位置和严重程度。生理评估是“格拉斯哥昏迷量表”、收缩压和呼吸频率的编码值。文中还给出了基于2569名钝器伤和穿透伤患者概况聚类生存率的聚类模型的生存-死亡预测值。该聚类模型的相对信息增益(R)为0.90。R是相对于完美预测器的预测值度量。其取值范围为0到1,值越高预测价值越好。该模型有26例假阴性(预测存活但实际死亡)和35例假阳性(预测死亡但实际存活),假阴性率为9.3%,假阳性率为1.4%,错误分类率为2.4%。R值和假阴性率特别值得注意,R值高于TRISS(一种基于创伤评分、损伤严重程度评分和患者年龄的综合指数)通常达到的30%-40%的值,假阴性率则远低于该值。同样值得注意的是,聚类独立于生存/死亡结局信息,并且即使患者年龄尚未纳入模型,仍取得了良好的结果。