Department 5 of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK; Natbrainlab, Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK; Sackler Institute for Translational Neurodevelopment, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.
Department 5 of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Neuroimage Clin. 2020;26:102168. doi: 10.1016/j.nicl.2020.102168. Epub 2020 Jan 25.
• In older healthy subjects, FA and MD show overall good test-retest reliability & reproducibility. • MD is sistematically more reproducible than FA across the entire brain anatomy. • FA is more reliable than MD in subcortical white matter regions. • In high reliability & low reproducibility regions, variability between subjects is high and statistical power is low. • In low reliability & high reproducibility regions, variability between subjects is low and statistical power is high.
• 在年龄较大的健康受试者中，FA 和 MD 总体上具有良好的测试-重测可靠性和可重复性。 • MD 在整个大脑解剖结构中比 FA 更具有可重复性。 • 在皮质下白质区域，FA 比 MD 更可靠。 • 在可靠性高、可重复性低的区域，个体之间的变异性较大，统计能力较低。 • 在可靠性低、可重复性高的区域，个体之间的变异性较小，统计能力较高。
