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衰弱在外科急症中的影响。四种衰弱量表的比较。

Impact of frailty in surgical emergencies. A comparison of four frailty scales.

作者信息

Arteaga Alejandro Sánchez, Aguilar Luis Tallón, González José Tinoco, Boza Ana Senent, Muñoz-Cruzado Virginia Durán, Ciuró Felipe Pareja, Ruíz Javier Padillo

机构信息

Universitary Hospital Virgen del Rocío, Avenida Manuel Siurot, 41013, Seville, Spain.

出版信息

Eur J Trauma Emerg Surg. 2021 Oct;47(5):1613-1619. doi: 10.1007/s00068-020-01314-3. Epub 2020 Feb 8.

Abstract

INTRODUCTION

Frailty is a geriatric syndrome, leading to declines in homeostatic reserve and physical resistance. It has been considered as a risk factor for falls, fractures, need of institutionalization, length of stay and mortality. Our aim was to evaluate the relationship between frailty, 30-day postoperative mortality and morbidity, for elderly patients undergoing surgical emergencies.

MATERIAL AND METHODS

Prospective, observational cohort Study (September 2017-April 2019), using four different frailty scales (Clinical Frailty Scale, FRAIL scale, TRST and Share-FI) as a risk factor of 30-day postoperative outcomes, for patients older than 70 years undergoing emergency surgery. We analyzed diagnoses, clinical examination at admission, surgical procedures, and postoperative outcomes during the first 30 days or until discharge.

RESULTS

92 patients were included, with a mean age was 78.7 years (SD 6.3). Frailty prevalence varied since 14.1% obtained using FRAIL scale, to 25%, 29.2% and 30.4%, from Clinical Frailty Scale, TRST and Share-FI, respectively. All four frailty scales show statistical differences to predict major complication and mortality in our sample. FRAIL scale showed the highest sensitivity-specificity pair to predict mortality in our sample (AUC = 0.870). TRST and FRAIL scales showed the strongest measure of association (OR 7.69 and 5.92, respectively) for major complications. Regarding need for admission to the ICU, hospital stay or reoperation rate, only FRAIL scale showed a statistically significant association.

CONCLUSION

Frailty represents a predictive marker of mortality and major complications, in surgical emergencies. FRAIL score, shows the strongest relationship with mortality and complications, compared to other frailty scales.

摘要

引言

衰弱是一种老年综合征,会导致体内稳态储备和身体抵抗力下降。它被认为是跌倒、骨折、需要入住机构、住院时间和死亡率的危险因素。我们的目的是评估老年急诊手术患者衰弱与术后30天死亡率和发病率之间的关系。

材料与方法

前瞻性观察队列研究(2017年9月至2019年4月),使用四种不同的衰弱量表(临床衰弱量表、衰弱量表、TRST和Share-FI)作为70岁以上接受急诊手术患者术后30天结局的危险因素。我们分析了诊断、入院时的临床检查、手术操作以及术后30天内或直至出院的术后结局。

结果

纳入92例患者,平均年龄为78.7岁(标准差6.3)。衰弱患病率各不相同,使用衰弱量表得出的患病率为14.1%,临床衰弱量表、TRST和Share-FI分别为25%、29.2%和30.4%。所有四种衰弱量表在预测我们样本中的主要并发症和死亡率方面均显示出统计学差异。衰弱量表在我们的样本中显示出预测死亡率的最高灵敏度-特异性对(AUC = 0.870)。TRST和衰弱量表对主要并发症显示出最强的关联度(分别为OR 7.69和5.9292)。关于入住重症监护病房的需求、住院时间或再次手术率,只有衰弱量表显示出统计学上的显著关联。

结论

在外科急诊中,衰弱是死亡率和主要并发症的预测指标。与其他衰弱量表相比,衰弱评分与死亡率和并发症的关系最为密切。

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