Silva Erika, Schumacher John, Passler Thomas
Facultad de Ciencias Clinicas Veterinarias, Instituto de Ciencias Clinicas Veterinarias, Universidad Austral de Chile, Valdivia, Chile.
Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Front Vet Sci. 2020 Jan 23;6:478. doi: 10.3389/fvets.2019.00478. eCollection 2019.
Orchiectomy is performed in some species using only sedation and local anesthesia to decrease the expense of performing the procedure using general anesthesia. The objective of this study was to determine if dogs can be castrated safely and painlessly by using only sedation and local anesthesia. After dogs were sedated with intramuscularly administered xylazine (1 mg/kg) and subanesthetic ketamine (1 mg/kg), testes and skin were anesthetized with 2% lidocaine (6 mg/kg, total dose) buffered with sodium bicarbonate. Systolic, diastolic, and mean blood pressures; heart and respiratory rates; and movement scores were determined before and during surgery when manipulations were most likely to cause pain. No dog reacted substantially to injection of the combination of sedatives, and no dog reacted noticeably to injection of lidocaine. During surgery, the average heart rate was reduced from baseline by 40-60 beats per minute, and the average respiratory rate was reduced by ~10 breaths per minute. An overall reduction of arterial blood pressures was observed. All but one dog moved purposely in response to a toe pinch at the end of surgery. We found that sedating dogs intramuscularly with xylazine and a sub-anesthetic dose of ketamine and administering lidocaine at the incision site and intratesticularly allowed dogs to be castrated humanely and avoided the expense of general anesthesia and the need for hospitalization.
在某些物种中,睾丸切除术仅使用镇静剂和局部麻醉进行,以降低使用全身麻醉进行该手术的费用。本研究的目的是确定仅使用镇静剂和局部麻醉是否能安全无痛地阉割犬类。在用肌肉注射赛拉嗪(1毫克/千克)和亚麻醉剂量的氯胺酮(1毫克/千克)对犬进行镇静后,用2%利多卡因(6毫克/千克,总剂量)加碳酸氢钠缓冲液对睾丸和皮肤进行麻醉。在手术前以及手术中最有可能引起疼痛的操作过程中,测定收缩压、舒张压和平均血压、心率和呼吸频率以及运动评分。没有一只犬对注射镇静剂组合有明显反应,也没有一只犬对注射利多卡因有明显反应。在手术过程中,平均心率比基线降低了每分钟40 - 60次,平均呼吸频率降低了约每分钟10次。观察到动脉血压总体下降。除了一只犬外,所有犬在手术结束时对脚趾挤压都有故意移动反应。我们发现,用赛拉嗪和亚麻醉剂量的氯胺酮对犬进行肌肉注射镇静,并在切口部位和睾丸内注射利多卡因,能够人道地阉割犬类,避免了全身麻醉的费用和住院需求。