Psychological & Brain Sciences, Indiana University Bloomington, Bloomington, Indiana.
Program in Neuroscience, Indiana University Bloomington.
J Pers Disord. 2021 Aug;35(4):513-537. doi: 10.1521/pedi_2020_34_466. Epub 2020 Feb 10.
Despite widespread use in schizophrenia-spectrum research, uncertainty remains around an empirically supported and theoretically meaningful factor structure of the Schizotypal Personality Questionnaire (SPQ). Current identified structures are limited by reliance on exclusively nonclinical samples. The current study compared factor structures of the SPQ in a sample of 335 nonpsychiatric individuals, 292 schizotypy-spectrum individuals (schizophrenia, schizoaffective disorder, or schizotypal personality disorder), and the combined group ( = 627). Unidimensional, correlated, and hierarchical models were assessed in addition to a bifactor model, wherein subscales load simultaneously onto a general factor and a specific factor. The best-fitting model across samples was a two-specific factor bifactor model, consistent with the nine symptom dimensions of schizotypy as primarily a direct manifestation of a unitary construct. Such findings, for the first time demonstrated in a clinical sample, have broad implications for transdiagnostic approaches, including reifying schizotypy as a construct underlying diverse manifestations of phenomenology across a wide range of severity.
尽管在精神分裂症谱系研究中广泛应用，但对精神分裂症人格问卷（SPQ）的经验支持和理论意义上有意义的因素结构仍然存在不确定性。目前确定的结构受到仅依赖非临床样本的限制。本研究在 335 名非精神病个体、292 名精神分裂症谱系个体（精神分裂症、分裂情感障碍或精神分裂症人格障碍）和合并组（=627 名）中比较了 SPQ 的因子结构。除了双因素模型外，还评估了单维、相关和层次模型，其中分量表同时加载到一般因素和特定因素上。在所有样本中，最佳拟合模型是双因素双因素模型，这与精神分裂症的九个症状维度一致，主要是单一结构的直接表现。这些首次在临床样本中证明的发现，对跨诊断方法具有广泛的意义，包括将精神分裂症作为一种现象学在广泛的严重程度上表现出不同表现的潜在结构。
