Fresco Parkinson Center, Department of Parkinson's disease, Movement Disorders & Brain Injury Rehabilitation, 'Moriggia-Pelascini' Hospital - Gravedona ed Uniti, Como, 22015, Italy.
Fresco Parkinson Center, Villa Margherita, S. Stefano Riabilitazione, Vicenza, 36057, Italy.
Neurodegener Dis Manag. 2020 Feb;10(1):41-55. doi: 10.2217/nmt-2019-0025. Epub 2020 Feb 10.
Parkinson's disease (PD) results in a complex deterioration of motor behavior. Effective pharmacological or surgical treatments addressing the whole spectrum of both motor and cognitive symptoms are lacking. The cumulative functional impairment may have devastating socio-economic consequences on both patients and caregivers. Comprehensive models of care based on multidisciplinary approaches may succeed in better addressing the overall complexity of PD. Neurorehabilitation is a highly promising non-pharmacological intervention for managing PD. The scientific rationale beyond rehabilitation and its practical applicability remain to be established. In the present perspective, we aim to discuss the current evidence supporting integrated motor-cognitive and aerobic rehabilitation approaches for patients with PD while suggesting a practical framework to optimize this intervention in the next future.
帕金森病（PD）导致运动行为的复杂恶化。缺乏有效的药物或手术治疗来解决所有运动和认知症状。累积的功能障碍可能对患者和护理人员都产生毁灭性的社会经济后果。基于多学科方法的综合护理模式可能更成功地应对 PD 的整体复杂性。神经康复是一种很有前途的非药物干预措施，可用于治疗 PD。康复背后的科学原理及其实际适用性仍有待确定。在本观点中，我们旨在讨论支持 PD 患者综合运动认知和有氧运动康复方法的现有证据，同时提出一个实用框架，以在未来优化这一干预措施。
