Department of Emergency Medicine, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 8, 3010, Bern, Switzerland.
Medical Skills Lab, Charité Medical School Berlin, Berlin, Germany.
Scand J Trauma Resusc Emerg Med. 2020 Feb 10;28(1):11. doi: 10.1186/s13049-020-0707-2.
Guidelines recommend endotracheal intubation in trauma patients with a Glasgow coma scale (GCS) < 9 because of the loss of airway reflexes and consequential risk of airway obstruction. However, in patients with acute alcohol intoxication guidelines are not clear. Thus, we aimed to determine the proportional incidence of intubation in alcohol intoxication and compare the clinical characteristics of intubated and non-intubated patients, as well as reasons for intubation in all patients and in the subgroup of patients with reduced GCS (< 9) but without traumatic brain injury.
We performed a retrospective analysis of all consultations to an urban ED in Switzerland that presented with an acute alcohol intoxication between 1st June 2012 and 31th Mai 2017. Patient and emergency consultations' characteristics, related injuries, intubation and reason for intubations were extracted. As a subgroup analysis, we analysed the patients with a GCS < 9 without a traumatic brain injury.
Of 3003 consultations included from 01.06.2012 to 31.05.2017, 68 were intubated, leading to a proportional incidence of 2.3% intubations in alcohol-intoxication. Intubated patients had a lower blood alcohol concentration (1.3 g/kg [IQR 1.0-2.2] vs. 1.6 g/kg [IQR1.1-2.2], p = 0.034) and less often suffered from chronic alcohol abuse (1183 [39.4%] patients vs. 14 [20.6%], p = 0.001) than non-intubated patients. Patients with trauma were intubated more often (33 patients [48.5%] vs. 742 [25.3%], p < 0.001). In subgroup analysis, 110/145 patients (74.3%) were not intubated; again, more intubated patients had a history of trauma (9 patients [25.7%] vs. 10 [9.1%], p = 0.011).
Intubation in alcohol-intoxicated patients is rare and, among intoxicated patients with GCS < 9, more than two thirds were not intubated in our study - without severe complications. Trauma in general, independent of the history of a traumatic brain injury, and a missing history of chronic alcohol abuse are associated with intubation, but not with blood alcohol concentration. Special caution is required for intoxicated patients with trauma or other additional intoxications or diseases.
由于气道反射丧失和随之而来的气道阻塞风险,指南建议格拉斯哥昏迷量表(GCS)<9 的创伤患者进行气管插管。然而,对于急性酒精中毒患者,指南并不明确。因此,我们旨在确定酒精中毒患者中插管的比例,并比较插管和未插管患者的临床特征,以及所有患者和 GCS<9 但无创伤性脑损伤亚组患者插管的原因。
我们对 2012 年 6 月 1 日至 2017 年 5 月 31 日期间在瑞士一家城市急诊就诊的所有急性酒精中毒患者进行了回顾性分析。提取患者和急诊就诊的特征、相关损伤、插管和插管原因。作为亚组分析,我们分析了 GCS<9 且无创伤性脑损伤的患者。
2012 年 6 月 1 日至 2017 年 5 月 31 日期间共纳入 3003 例就诊患者,其中 68 例患者插管,导致酒精中毒患者插管的比例为 2.3%。插管患者的血液酒精浓度较低(1.3 g/kg [IQR 1.0-2.2] 与 1.6 g/kg [IQR 1.1-2.2],p=0.034),慢性酒精滥用的发生率较低(1183 例[39.4%]患者与 14 例[20.6%],p=0.001)。有创伤的患者更常插管(33 例[48.5%]与 742 例[25.3%],p<0.001)。在亚组分析中,145 例患者中 110 例(74.3%)未插管;同样,更多的插管患者有创伤史(9 例[25.7%]与 10 例[9.1%],p=0.011)。
在酒精中毒患者中,插管很少见,在我们的研究中,GCS<9 的酒精中毒患者中,超过三分之二未插管,且没有严重并发症。总体上的创伤,独立于创伤性脑损伤的病史,以及无慢性酒精滥用史,与插管有关,但与血液酒精浓度无关。对于有创伤或其他合并中毒或疾病的醉酒患者,需要特别注意。