Suppr超能文献

肝包虫病的封闭性囊肿切除术:新标准。

Closed Cyst Resection for Liver Hydatid Disease: a New Standard.

机构信息

Department of Surgery and Liver Transplantation, Hôpital de la Timone, Marseille, France.

Department of Surgery, Hôpital Sainte Anne, Toulon, France.

出版信息

J Gastrointest Surg. 2021 Feb;25(2):436-446. doi: 10.1007/s11605-019-04509-1. Epub 2020 Feb 10.

Abstract

BACKGROUND

Although radical resections are recommended for the surgical management of liver hydatid disease (LHD), whether closed (CCR) or opened (OCR) cyst resections should be performed remains unclear. The aim of this study was to compare the postoperative and long-term outcomes of CCR and OCR for primary and recurrent LHD.

MATERIALS AND METHODS

Medical charts of patients who underwent surgery at a single centre were retrospectively reviewed and compared with respect to major postoperative complications and recurrence rates.

RESULTS

Seventy-nine CCRs and 37 OCRs were included. The major morbidity rates were 19% and 5% in the OCR and CCR groups, respectively (P = 0.036). In multivariate analysis, OCR (P = 0.030, OR = 5.37) and the operative time (P < 0.001, OR = 18.88) were the only independent predictors of major complications. The 5-year and 10-year recurrence rates were both 0% in the CCR group compared to 18% and 27%, respectively, in the OCR group (P < 0.001). The mean time to recurrence was 10.5 (± 8) years.

DISCUSSION

Closed cyst resection for LHD is a safe and effective approach with a low risk of recurrence. Considering that recurrence could appear more than 10 years after surgery, follow-up of patients should be adapted.

摘要

背景

尽管肝包虫病(LHD)的外科治疗推荐进行根治性切除术,但对于行闭合(CCR)或开放性(OCR)肝包虫囊肿切除术仍存在争议。本研究旨在比较原发性和复发性 LHD 行 CCR 和 OCR 的术后和长期结果。

材料和方法

回顾性分析单中心接受手术治疗的患者的病历,并比较主要术后并发症和复发率。

结果

共纳入 79 例 CCR 和 37 例 OCR。OCR 组和 CCR 组的主要并发症发生率分别为 19%和 5%(P=0.036)。多因素分析显示,OCR(P=0.030,OR=5.37)和手术时间(P<0.001,OR=18.88)是主要并发症的唯一独立预测因素。CCR 组的 5 年和 10 年复发率均为 0%,而 OCR 组分别为 18%和 27%(P<0.001)。复发的平均时间为 10.5(±8)年。

讨论

对于 LHD,行闭合肝包虫囊肿切除术是一种安全有效的方法,复发风险低。鉴于术后 10 年以上可能出现复发,应调整患者的随访策略。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验