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关节痛的存在会加重化脓性汗腺炎患者生活质量的下降。

Presence of arthralgia exacerbates decreased quality of life in hidradenitis suppurativa patients.

作者信息

Kremer Michael, Chang Tiffany C, Murina Andrea

机构信息

Department of Dermatology, Tulane University School of Medicine, New Orleans, LA.

出版信息

Dermatol Online J. 2019 Nov 15;25(11):13030/qt1b36n770.

PMID:32045157
Abstract

Hidradenitis suppurativa is characterized by chronic follicular occlusion that presents with recurrent nodules, inflamed abscesses, and scarring. Research has shown that these patients have a decreased quality of life. In addition to its psychosocial effects, hidradenitis suppurativa has recently been associated with joint pathology. In this study, we distributed a survey consisting of the Short Form 12 Health Survey, used for assessing health outcomes, along with additional questions about joint pain to an online hidradenitis suppurativa support group in order to understand the effect of comorbid arthralgia on quality of life in this disease. The respondents in this study had significantly reduced physical health composite scores-12 (PCS-12), (35.8 versus 50, P<0.001) and mental health composite scores-12 (MCS-12), (33.7 versus 50, P<0.001) scores compared to the general population. Additionally, patients reporting severe arthralgia had significantly lower PCS-12 (32.3 versus 36.5; P<0.05) and MCS-12 (33.3 versus 40.5; P<0.001) scores compared to those with mild arthralgia. Despite the effect of comorbid arthralgia on quality of life, only 11% reported having been asked about joint pain by their dermatologist. Routine screening questions concerning associated arthralgia and diminished quality of life may be helpful during clinician assessment and treatment of hidradenitis suppurativa patients.

摘要

化脓性汗腺炎的特征是慢性毛囊阻塞,表现为反复发作的结节、炎性脓肿和瘢痕形成。研究表明,这些患者的生活质量下降。除了其心理社会影响外,化脓性汗腺炎最近还与关节病变有关。在本研究中,我们向一个在线化脓性汗腺炎支持小组发放了一份调查问卷,其中包括用于评估健康结果的简短健康调查问卷12项(Short Form 12 Health Survey)以及关于关节疼痛的附加问题,以了解合并关节痛对该疾病患者生活质量的影响。与普通人群相比,本研究中的受访者的身体健康综合评分-12(PCS-12)(35.8对50,P<0.001)和心理健康综合评分-12(MCS-12)(33.7对50,P<0.001)显著降低。此外,与轻度关节痛患者相比,报告有严重关节痛的患者的PCS-12(32.3对36.5;P<0.05)和MCS-12(33.3对40.5;P<0.001)评分显著更低。尽管合并关节痛对生活质量有影响,但只有11%的患者报告皮肤科医生曾询问过他们的关节疼痛情况。在临床医生评估和治疗化脓性汗腺炎患者时,关于相关关节痛和生活质量下降的常规筛查问题可能会有所帮助。

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引用本文的文献

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Br J Dermatol. 2024 Oct 17;191(5):839-841. doi: 10.1093/bjd/ljae251.
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Burden of Hidradenitis Suppurativa: A Systematic Literature Review of Patient Reported Outcomes.化脓性汗腺炎的负担:患者报告结局的系统文献综述
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