Clinical Epidemiology Unit, IDI-IRCCS, Via dei Monti di Creta, 104, 00167, Rome, Italy.
1st Dermatological Unit, IDI-IRCCS, Rome, Italy.
Arch Dermatol Res. 2021 Jan;313(1):41-47. doi: 10.1007/s00403-020-02063-4. Epub 2020 Apr 8.
Hidradenitis suppurativa (HS) has a considerable impact on quality of life. Despite comparisons of health status between HS patients and the general population have been done, there is a need to make more meaningful comparisons, such as age-specific ones. The objective of the study was to compare age-specific physical and mental health status in Italian patients with HS to that of a representative sample of the Italian general population. We conducted a cross-sectional, observational study on consecutive HS patients. Patients' health status was measured using the 36-item Short Form Health Survey (SF-36) and in the general population using the 12-item version (SF-12). The mean scores of the physical component summary (PCS) and the mental component summary (MCS) from the two instruments were graphically compared in different age categories according to sex and clinical severity. Data were complete for 298 HS patients. Young patients with HS reported a physical and mental health status similar to that of elderly people from the general population. Even HS patients with mild-to-moderate clinical severity had a consistently worse health status than the reference population. In conclusion, HS deeply affects patients' physical and mental status, starting from a very young age. An early intervention is advisable, not only with pharmacological treatment, but also with an appropriate discussion and interaction with the patient to focus on the aspects that would reduce the psychosocial impact of their condition.
化脓性汗腺炎（HS）对生活质量有很大影响。尽管已经对 HS 患者和一般人群的健康状况进行了比较，但仍需要进行更有意义的比较，例如按年龄划分的比较。本研究的目的是比较意大利 HS 患者的特定年龄的生理和心理健康状况与代表性的意大利一般人群样本。我们对连续的 HS 患者进行了横断面、观察性研究。使用 36 项简短健康调查问卷（SF-36）和 12 项简短健康调查问卷（SF-12）来测量患者的健康状况。根据性别和临床严重程度，根据不同年龄组，将两种仪器的生理成分综合评分（PCS）和心理成分综合评分（MCS）的平均值进行图形比较。共有 298 名 HS 患者的数据完整。年轻的 HS 患者报告的生理和心理健康状况与来自一般人群的老年人相似。即使是临床严重程度为轻度至中度的 HS 患者，其健康状况也始终比参考人群差。总之，HS 从很年轻的时候就严重影响患者的生理和心理状态。建议早期干预，不仅要进行药物治疗，还要与患者进行适当的讨论和互动，重点关注减轻其病情对社会心理影响的方面。
