Harada J, Horiguchi T, Oki K, Miyamoto H, Osada T
Gan To Kagaku Ryoho. 1987 Sep;14(9):2697-702.
Skin testing with intradermally injected Su-Polysaccharide (extracted from Su strain Streptococcus bacteria) was performed in 41 cases of lung cancer. Su-polysaccharide skin test results were correlated, to some extent, with the patient's age, clinical stage and performance status and showed a similar trend to the simultaneously performed PPD skin test. These results suggested the potential usefulness of Su-Polysaccharide skin test results as one of the parameters of immunological status of patients with lung cancer. It was also demonstrated that skin reaction to Su-Polysaccharide was increased specifically after OK-432 immunotherapy and was well correlated with the prognosis of the disease. The Su-Polysaccharide skin test was thus considered to be a useful parameter for monitoring the immune response to OK-432 immunotherapy in lung cancer and also one of the parameters of prognostic value.
对41例肺癌患者进行了皮内注射苏多糖（从苏型链球菌中提取）的皮肤试验。苏多糖皮肤试验结果在一定程度上与患者的年龄、临床分期和身体状况相关，并且与同时进行的结核菌素皮肤试验呈现相似趋势。这些结果表明，苏多糖皮肤试验结果有可能作为肺癌患者免疫状态的参数之一。还证实，在进行溶链菌制剂免疫治疗后，对苏多糖的皮肤反应会特异性增强，并且与疾病预后密切相关。因此，苏多糖皮肤试验被认为是监测肺癌患者对溶链菌制剂免疫治疗免疫反应的有用参数，也是具有预后价值的参数之一。
