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[OK-432治疗胃肠道癌患者免疫反应皮肤试验(SU-PS)的临床意义]

[Clinical significance of a skin test (SU-PS) for immune responses in patients with gastrointestinal cancer treated with OK-432].

作者信息

Miyamoto Y, Takeshita M, Izuo M

出版信息

Gan To Kagaku Ryoho. 1986 Oct;13(11):3229-35.

PMID:3777960
Abstract

Using the Su-PS skin test, an attempt was made to evaluate whether or not this reaction could become a useful immune parameter in patients with gastrointestinal cancer. The conclusions were as follows: Late-stage patients with gastric cancer showed a weak response in the Su-PS skin test when examined preoperatively. The skin reaction to Su-PS was shown to become stronger than in the PPD and PHA test when patients received OK-432 treatment. Patients with advanced cancer having longer survival (more than 7 months) showed stronger response in the Su-PS skin test that patients having short survival (less than 6 months). It was suggested that the Su-PS skin test was useful for evaluating the immune response to OK-432 treatment.

摘要

利用Su-PS皮肤试验,尝试评估这种反应能否成为胃肠癌患者有用的免疫参数。结论如下:胃癌晚期患者术前接受检查时,在Su-PS皮肤试验中表现出较弱的反应。当患者接受OK-432治疗时,对Su-PS的皮肤反应比在PPD和PHA试验中更强。生存期较长(超过7个月)的晚期癌症患者在Su-PS皮肤试验中的反应比生存期较短(少于6个月)的患者更强。有人提出,Su-PS皮肤试验有助于评估对OK-432治疗的免疫反应。

相似文献

1
[Clinical significance of a skin test (SU-PS) for immune responses in patients with gastrointestinal cancer treated with OK-432].[OK-432治疗胃肠道癌患者免疫反应皮肤试验(SU-PS)的临床意义]
Gan To Kagaku Ryoho. 1986 Oct;13(11):3229-35.
2
[Evaluation of immune status in gastric cancer using Su-Ps skin test].[利用苏氏皮肤试验评估胃癌患者的免疫状态]
Gan To Kagaku Ryoho. 1984 Oct;11(10):2221-6.
3
[Role of immune skin reactions in progressive lung cancer during the administration of OK-432--relation to reactions to DNCB, PPD and Su-PS].(在使用OK-432治疗期间免疫皮肤反应在进展期肺癌中的作用——与对二硝基氯苯、结核菌素纯蛋白衍生物和链球菌变应原提取物的反应的关系)
Gan To Kagaku Ryoho. 1987 Jan;14(1):61-70.
4
[Clinical significance of Su-polysaccharide (Su-PS) skin test in patients with primary lung cancer treated with chemotherapy and administration of OK-432, with special reference to the therapeutic effect and prognosis].[舒多糖(Su-PS)皮肤试验在接受化疗及注射OK-432治疗的原发性肺癌患者中的临床意义,特别涉及治疗效果和预后]
Gan To Kagaku Ryoho. 1990 Mar;17(3 Pt 2):468-74.
5
[Su-polysaccharide skin test and immunotherapy with OK-432 in postoperative gastric cancer--the effect of a splenectomy].[香菇多糖皮肤试验及OK-432在胃癌术后的免疫治疗——脾切除术的影响]
Gan No Rinsho. 1988 Nov;34(14):1965-8.
6
[The Su-polysaccharide skin test in lung cancer].[香菇多糖皮肤试验在肺癌中的应用]
Gan To Kagaku Ryoho. 1987 Sep;14(9):2697-702.
7
[Immunotherapy of terminal-stage malignant tumors with the immunopotentiator OK-432--a comparison between SU-PS test-responder and -nonresponder patients].用免疫增强剂OK-432对晚期恶性肿瘤进行免疫治疗——SU-PS试验反应者与无反应者患者的比较
Gan No Rinsho. 1987 Jun;33(7):815-21.
8
[Relation between prognosis and the Su-PS skin reaction in patients with non-resected primary lung cancer receiving OK-432].[未切除原发性肺癌患者接受OK-432治疗后预后与Su-PS皮肤反应的关系]
Gan To Kagaku Ryoho. 1987 Nov;14(11):3050-7.
9
[Clinical studies on the reaction of the skin to various doses of Su-polysaccharide in cancer patients].[癌症患者皮肤对不同剂量舒多糖反应的临床研究]
Gan To Kagaku Ryoho. 1985 Feb;12(2):245-9.
10
[The effect of OK-432 in the treatment of primary lung cancer].[溶链菌制剂对原发性肺癌的治疗作用]
Gan To Kagaku Ryoho. 1987 Apr;14(4):1051-6.