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[OK-432治疗胃肠道癌患者免疫反应皮肤试验(SU-PS)的临床意义]

[Clinical significance of a skin test (SU-PS) for immune responses in patients with gastrointestinal cancer treated with OK-432].

作者信息

Miyamoto Y, Takeshita M, Izuo M

出版信息

Gan To Kagaku Ryoho. 1986 Oct;13(11):3229-35.

PMID:3777960
Abstract

Using the Su-PS skin test, an attempt was made to evaluate whether or not this reaction could become a useful immune parameter in patients with gastrointestinal cancer. The conclusions were as follows: Late-stage patients with gastric cancer showed a weak response in the Su-PS skin test when examined preoperatively. The skin reaction to Su-PS was shown to become stronger than in the PPD and PHA test when patients received OK-432 treatment. Patients with advanced cancer having longer survival (more than 7 months) showed stronger response in the Su-PS skin test that patients having short survival (less than 6 months). It was suggested that the Su-PS skin test was useful for evaluating the immune response to OK-432 treatment.

摘要

利用Su-PS皮肤试验,尝试评估这种反应能否成为胃肠癌患者有用的免疫参数。结论如下:胃癌晚期患者术前接受检查时,在Su-PS皮肤试验中表现出较弱的反应。当患者接受OK-432治疗时,对Su-PS的皮肤反应比在PPD和PHA试验中更强。生存期较长(超过7个月)的晚期癌症患者在Su-PS皮肤试验中的反应比生存期较短(少于6个月)的患者更强。有人提出,Su-PS皮肤试验有助于评估对OK-432治疗的免疫反应。

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