Obata S, Matsuzaki H, Nishimura H, Kawakita M, Takatsuki K
Second Department of Internal Medicine, Kumamoto University Medical School.
Jpn J Clin Oncol. 1988 Dec;18(4):335-42.
Gastroduodenal endoscopic examinations were performed on 15 patients with adult T-cell leukemia (ATL). Twelve had the disease in acute form, two in chronic form and one patient was in crisis. Eight patients had gastroduodenal lesions, four esophageal candidiasis, three gastric infiltration and two duodenal ATL-cell infiltration. Four out of the five patients who had the gastroduodenal ATL-cell infiltration complained of gastroduodenal symptoms such as anorexia, upper abdominal pain, diarrhea and melena. Our observations suggested that these gastroduodenal symptoms were related to the gastroduodenal ATL-cell infiltration. Esophageal candidiasis in ATL could be related to immunodeficiency.
对15例成人T细胞白血病(ATL)患者进行了胃十二指肠内镜检查。其中12例为急性发病,2例为慢性发病,1例处于危象期。8例有胃十二指肠病变,4例有食管念珠菌病,3例有胃浸润,2例有十二指肠ATL细胞浸润。5例有胃十二指肠ATL细胞浸润的患者中,4例诉说有胃十二指肠症状,如厌食、上腹痛、腹泻和黑便。我们的观察表明,这些胃十二指肠症状与胃十二指肠ATL细胞浸润有关。ATL患者的食管念珠菌病可能与免疫缺陷有关。