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太极拳与常规运动对早期或轻度帕金森病患者的影响:一项回顾性队列分析。

Tai Chi versus routine exercise in patients with early- or mild-stage Parkinson's disease: a retrospective cohort analysis.

机构信息

Department of Neurology, Gaomi People's Hospital, Gaomi, Shandong, China.

Department of Neurosurgery, Gaomi People's Hospital, Gaomi, Shandong, China.

出版信息

Braz J Med Biol Res. 2020 Feb 10;53(2):e9171. doi: 10.1590/1414-431X20199171. eCollection 2020.

DOI:10.1590/1414-431X20199171
PMID:32049101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7013627/
Abstract

Parkinson's disease cannot be cured but symptoms can be improved by making use of physical therapy. The objective of the study was to compare the effect of routine exercises and Tai Chi on physical and clinical performance in elderly people suffering from Parkinson's disease. Data from interviews, physical and clinical performance, and levodopa consumption of 500 patients with confirmed Parkinson's disease (severity level I to III) were collected and analyzed. Participants who received 80 min/day Tai Chi 3 times/week for 2 months were included in the Tai Chi (TC) group (n=250) and those who received 90 min/day routine exercise 3 times/week for 2 months were included in routine exercise (RE) group (n=250). Timed up-and-go, 50-foot speed walk, and functional reach were improved by Tai Chi and routine exercise (P<0.05 for all) but intensities of Tai Chi for improvement of such parameters was higher than routine exercise. Incidence of falls was decreased by both physical therapies (P<0.05 for all) but more for the TC group (P<0.0001, q=38.512). In the TC group, at the end of follow-up, 22 (9%) patients were successful in withdrawal of levodopa treatment. Also, the dose of levodopa was decreased in patients of the TC group who had to continue levodopa. Tai Chi had the potential to slow down the progression of symptoms of Parkinson's disease and delayed the introduction of levodopa (level of evidence: III).

摘要

帕金森病无法治愈,但通过物理疗法可以改善症状。本研究的目的是比较常规运动和太极拳对帕金森病老年患者身体和临床表现的影响。收集并分析了 500 名确诊帕金森病患者(严重程度 I 至 III 级)的访谈、身体和临床表现以及左旋多巴的使用数据。接受 80 分钟/天、每周 3 次、持续 2 个月的 3 次/周太极拳锻炼的患者被纳入太极拳(TC)组(n=250),接受 90 分钟/天、每周 3 次、持续 2 个月的常规运动锻炼的患者被纳入常规运动(RE)组(n=250)。太极拳和常规运动均可改善计时起立行走、50 英尺速走和功能伸展(P<0.05),但太极拳改善这些参数的强度更高。两种物理治疗均可降低跌倒发生率(所有 P<0.05),但太极拳组降低更为显著(P<0.0001,q=38.512)。在 TC 组中,在随访结束时,有 22 名(9%)患者成功停止了左旋多巴治疗。此外,TC 组继续服用左旋多巴的患者的左旋多巴剂量也减少了。太极拳有可能减缓帕金森病症状的进展并延迟左旋多巴的引入(证据水平:III)。

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