Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China
J Neurol Neurosurg Psychiatry. 2024 Feb 14;95(3):222-228. doi: 10.1136/jnnp-2022-330967.
Tai Chi has shown beneficial effects on the motor and non-motor symptoms of Parkinson's disease (PD), but no study has reported the effect of long-term Tai Chi training.
To examine whether long-term Tai Chi training can maintain improvement in patients with PD.
Cohorts of patients with PD with Tai Chi training (n=143) and patients with PD without exercise as a control group (n=187) were built from January 2016. All subjects were assessed at baseline and in November 2019, October 2020 and June 2021. A logarithmic linear model was used to analyse rating scales for motor and non-motor symptoms. The need to increase antiparkinsonian therapies was presented as a Kaplan-Meier plot and as a box plot. The bootstrap method was used to resample for statistical estimation.
Tai Chi training reduced the annual changes in the deterioration of the Unified Parkinson's Disease Rating Scale and delayed the need for increasing antiparkinsonian therapies. The annual increase in the levodopa equivalent daily dosage was significantly lower in the Tai Chi group. Moreover, patients benefited from Tai Chi training in motor symptoms, non-motor symptoms and complications.
Tai Chi training has a long-term beneficial effect on PD, with an improvement in motor and non-motor symptoms and reduced complications.
NCT05447975.
太极拳已被证明对帕金森病（PD）的运动和非运动症状具有有益影响，但尚无研究报告长期太极拳训练的效果。
检验长期太极拳训练是否能维持 PD 患者的改善。
从 2016 年 1 月开始，建立了接受太极拳训练的 PD 患者队列（n=143）和不进行运动作为对照组的 PD 患者队列（n=187）。所有患者在基线时和 2019 年 11 月、2020 年 10 月和 2021 年 6 月进行评估。对数线性模型用于分析运动和非运动症状的评分量表。抗帕金森病治疗的增加需要呈现为 Kaplan-Meier 图和箱线图。使用自举方法进行重采样以进行统计估计。
太极拳训练减少了统一帕金森病评定量表恶化的年变化率，并延缓了抗帕金森病治疗增加的需要。太极拳组的左旋多巴等效日剂量年增长率显著降低。此外，患者从太极拳训练中受益于运动症状、非运动症状和并发症。
太极拳训练对 PD 具有长期的有益影响，可改善运动和非运动症状并减少并发症。
NCT05447975。
