Berman Ye'elah, Ibiebele Ibinabo, Patterson Jillian A, Randall Deborah, Ford Jane B, Nippita Tanya, Morris Jonathan M, Davies-Tuck Miranda L, Torvaldsen Siranda
The University of Sydney Northern Clinical School, Women and Babies Research, St Leonards, New South Wales, Australia.
NSW Biostatistics Training Program, NSW Ministry of Health, Sydney, New South Wales, Australia.
Aust N Z J Obstet Gynaecol. 2020 Jun;60(3):425-432. doi: 10.1111/ajo.13085. Epub 2019 Nov 5.
Research suggests that in Australia, maternal region of birth is a risk factor for stillbirth.
We aimed to examine the relationship between stillbirth and maternal region of birth in New South Wales (NSW), Australia from 2004 to 2015.
Adjusted logistic regression was used to determine odds of stillbirth by maternal region of birth, compared with Australian or New Zealand-born (AUS/NZ-born) women. Intervention rates (induction or pre-labour caesarean) by maternal region of birth, over time, were also examined. Interaction terms were used to assess change in relative odds of stillbirth, over two time periods (2004-2011 and 2012-2015).
There were 944 457 singleton births ≥24 weeks gestation that met the study inclusion criteria and 3221 of these were stillbirths, giving a stillbirth rate of 3.4 per 1000 births. After adjustment for confounders, South Asian (adjusted odds ratio (aOR) 1.42, 95% CI 1.24-1.62), Oceanian (aOR 1.45, 95% CI 1.17-1.80) and African (aOR 1.46, 96% CI 1.19-1.80) born women had significantly higher odds of stillbirth that AUS/NZ-born women. Intervention rates increased from the earlier to the later time period by 13.1% across the study population, but the increase was larger in African and South Asian-born women (18.1% and 19.6% respectively) than AUS/NZ-born women (11.2%). There was a significant interaction between ethnicity and time period for South Asian-born women in the all-births model, with their stillbirth rates becoming closer to AUS/NZ-born women in the later period.
South Asian, African and Oceanian maternal region of birth are independent risk factors for stillbirth in NSW.
研究表明,在澳大利亚,产妇的出生地是死产的一个风险因素。
我们旨在研究2004年至2015年澳大利亚新南威尔士州(NSW)死产与产妇出生地之间的关系。
采用调整后的逻辑回归来确定按产妇出生地划分的死产几率,并与澳大利亚或新西兰出生(澳新出生)的女性进行比较。还研究了不同时间按产妇出生地划分的干预率(引产或临产前剖宫产)。使用交互项来评估两个时间段(2004 - 2011年和2012 - 2015年)死产相对几率的变化。
有944457例孕周≥24周的单胎分娩符合研究纳入标准,其中3221例为死产,死产率为每1000例分娩中有3.4例。在对混杂因素进行调整后,南亚出生(调整后的优势比[aOR]为1.42,95%置信区间[CI]为1.24 - 1.62)、大洋洲出生(aOR为1.45, 95% CI为1.17 - 1.80)和非洲出生(aOR为1.46, 96% CI为1.19 - 1.80)的女性死产几率显著高于澳新出生的女性。在整个研究人群中,干预率从早期到后期增加了13.1%,但非洲和南亚出生的女性增加幅度更大(分别为18.1%和19.6%),高于澳新出生的女性(1 .2%)。在所有分娩模型中,南亚出生的女性在种族和时间段之间存在显著交互作用,她们在后期的死产率更接近澳新出生的女性。
在新南威尔士州,南亚、非洲和大洋洲产妇出生地是死产的独立风险因素。