Jeon Soo Ji, Jung Younhea, Jung Chang-Sub, Park Hae-Young Lopilly, Park Chan Kee
Department of Ophthalmology, Seoul St. Mary's Hospital.
Department of Ophthalmology, Yeouido St. Mary's Hospital.
Medicine (Baltimore). 2020 Feb;99(7):e19149. doi: 10.1097/MD.0000000000019149.
This study aimed to compare various visual function parameters for evaluating the quality of life (QOL) of patients with advanced glaucoma with low vision.In total, 44 eyes of advanced glaucoma patients with low vision were included in this cross-sectional study. A moving pattern edge band program was used to assess edge detection ability and the low vision quality-of-life (LVQOL) questionnaire was used for evaluating QOL scores of subjects. Correlation analyses between QOL scores and visual functional parameters including pattern edge band unit, visual acuity (VA), and Mean deviation (MD) of perimetry were performed. The areas under receiver operating characteristic curves (AUROCs) of diverse visual functional parameters were calculated.VA and pattern edge band unit were related to LVQOL score in all subjects. For patients with a decimal VA lower than 0.1, only the pattern edge band showed a significant correlation with the QOL associated with distant activities (P = .031). However, the MD of perimetry was not related to the QOL score. After sorting subjects into 2 groups according to the LVQOL score, VA and pattern edge band unit were significantly different (P < .01 and P = .029, respectively). The AUROC for edge detection ability using pattern edge band was higher than MD of perimetry.Assessment of edge detection ability using pattern edge band was meaningful for predicting QOL associated with visual performance in patients with far-advanced glaucoma. For these patients, edge detection could be used as an additional parameter for visual function with traditional VA and perimetry.
本研究旨在比较各种视觉功能参数，以评估晚期青光眼低视力患者的生活质量（QOL）。在这项横断面研究中，共纳入了44只晚期青光眼低视力患者的眼睛。使用移动模式边缘带程序评估边缘检测能力，并使用低视力生活质量（LVQOL）问卷评估受试者的QOL得分。对QOL得分与包括模式边缘带单位、视力（VA）和视野平均偏差（MD）在内的视觉功能参数进行相关性分析。计算不同视觉功能参数的受试者工作特征曲线下面积（AUROCs）。在所有受试者中，VA和模式边缘带单位与LVQOL得分相关。对于小数视力低于0.1的患者，只有模式边缘带与远距离活动相关的QOL显示出显著相关性（P = 0.031）。然而，视野MD与QOL得分无关。根据LVQOL得分将受试者分为两组后，VA和模式边缘带单位有显著差异（分别为P < 0.01和P = 0.029）。使用模式边缘带进行边缘检测能力的AUROC高于视野MD。使用模式边缘带评估边缘检测能力对于预测晚期青光眼患者与视觉表现相关的QOL具有重要意义。对于这些患者，边缘检测可作为传统VA和视野检查之外的视觉功能附加参数。
