Streetlab, Institut de la Vision.
Department of Ophthalmology, Ninth People's Hospital, Shanghai JiaoTong University School of Medicine.
J Glaucoma. 2020 Oct;29(10):970-974. doi: 10.1097/IJG.0000000000001597.
Glaucoma patients displayed alterations in their quality of life (QoL) and their ability to perform activities of daily living. The visual field (VF) of the worse eye might serve as a good marker for QoL evaluation.
The purpose of this study was to explore the correlations between VF defects, performance in simulated activities of daily living, and subjective evaluation of QoL in glaucoma patients.
Thirty-two patients with glaucoma and 10 age-matched control subjects were included. All participants answered a QoL questionnaire and underwent an assessment of visual function including monocular and binocular best-corrected visual acuity, binocular contrast sensitivity test (LogCS), and monocular and binocular VF. All subjects also carried out a series of simulated activities of daily living in a controlled environment.
Glaucoma patients had lower QoL scores compared with controls for the composite score, near and distance activities, social functioning, mental health, role difficulties, dependency, and color vision. With regard to performance in the simulated mobility task, the number of mobility incidents was higher for glaucoma patients than for control subjects. For the reaching and grasping tasks, the overall movement duration for small objects was significantly longer in glaucoma patients compared with controls. The VF mean deviation of the worse eye was correlated with most of the QoL subscores. Mobility incidents as well as the reaching and grasping task parameters were not significantly correlated with QoL scores.
Glaucoma patients showed an alteration of performance in simulated daily living activities, associated with a decreased QoL. There was no clear correlation between alterations in QoL and ability to perform activities of daily living. The QoL related to vision was mostly correlated to the visual function of the worse eye.
青光眼患者的生活质量（QoL）和日常活动能力发生改变。较差眼的视野（VF）可能是 QoL 评估的良好标志物。
本研究旨在探讨青光眼患者的 VF 缺损、模拟日常生活活动能力以及主观 QoL 评估之间的相关性。
纳入 32 名青光眼患者和 10 名年龄匹配的对照者。所有参与者均回答了一份 QoL 问卷，并接受了单眼和双眼最佳矫正视力、双眼对比敏感度测试（LogCS）以及单眼和双眼 VF 的评估。所有受试者还在受控环境中进行了一系列模拟日常生活活动。
与对照组相比，青光眼患者的综合评分、近距和远距离活动、社会功能、心理健康、角色困难、依赖性和色觉的 QoL 评分较低。在模拟移动任务中，青光眼患者的移动事件次数高于对照组。对于伸手和抓握任务，青光眼患者抓取小物体的总运动时间明显长于对照组。较差眼的 VF 平均偏差与大多数 QoL 子评分相关。移动事件以及伸手和抓握任务参数与 QoL 评分无显著相关性。
青光眼患者的模拟日常生活活动能力发生改变，生活质量下降。QoL 的改变与日常生活活动能力之间没有明确的相关性。与视力相关的 QoL 主要与较差眼的视力功能相关。
