Back L H, Back M R, Kwack E Y, Crawford D W
Jet Propulsion Laboratory, California Institute of Technology, Pasadena 91109.
J Biomech Eng. 1988 Nov;110(4):300-9. doi: 10.1115/1.3108446.
Flow visualization and wall pressure measurements were made in a smooth reverse curvature model that conformed to the gentle "s" shape of a left femoral artery angiogram of a patient in a clinical trial. Observed lesion localization at the inner (lesser) curvatures appeared to be associated with secondary flows in the wall vicinity directed toward the inner curvatures that tended to reverse direction in the flow entering the reverse curvature region. Moderate flow resistance increases of about 20 percent above the Poiseuille flow relation were found at the higher physiological Reynolds numbers Re above about 600-700 and thus Dean numbers for steady flow. For pulsatile flow simulation, flow resistances did not increase up to the largest Re of 470 tested. Apparently, the large variations in velocity during the cardiac cycle disrupted the stronger secondary flow patterns observed at the higher Reynolds numbers for steady flow.
在一个符合临床试验中患者左股动脉血管造影柔和“s”形的光滑反向曲率模型中进行了流动可视化和壁面压力测量。在内侧（较小）曲率处观察到的病变定位似乎与壁面附近朝向内侧曲率的二次流有关，这些二次流在进入反向曲率区域的流动中往往会反向。在高于约600 - 700的较高生理雷诺数Re以及因此对于稳定流的迪恩数时，发现流动阻力比泊肃叶流动关系增加了约20%。对于脉动流模拟，在测试的最大Re为470时流动阻力并未增加。显然，心动周期中速度的大幅变化扰乱了在较高雷诺数下稳定流中观察到的更强的二次流模式。
