Back L H, Kwack E Y, Crawford D W
Jet Propulsion Laboratory, California Institute of Technology, Pasadena 91109.
J Biomech Eng. 1988 Nov;110(4):310-9. doi: 10.1115/1.3108447.
Flow visualization and pressure measurements were made for physiological conditions in a model derived from a femoral angiogram of a patient with lesion localization on the inner curvature wall and with vessel taper. Effects of curvature and taper were evaluated separately in other curved, tapered, smooth and straight, tapered, smooth models. Double helical secondary flow patterns were modified by plaque on the inner wall, and flow separations were observed between plaques at higher flow rates and Reynolds numbers. Pressure drop data for the plaque simulation model were similar in trend with Reynolds number as for the smooth model, but flow resistances were 25 to 40 percent higher. Significant pressure drops were measured due to the mild taper which could be estimated from momentum considerations, and smaller increased pressure drops were found due to curvature effects at the higher Dean numbers. Flow resistances for in vivo pulsatile flow simulation were about 10 percent higher than for steady flow for the plaque model, whereas no differences were observed for the smooth model.
针对一名病变位于内曲率壁且血管呈锥形的患者的股动脉血管造影所构建的模型，进行了生理条件下的血流可视化和压力测量。分别在其他弯曲、锥形、光滑且笔直以及锥形、光滑的模型中评估了曲率和锥度的影响。双螺旋二次流模式因内壁斑块而改变，并且在较高流速和雷诺数下，在斑块之间观察到了流动分离。斑块模拟模型的压降数据与光滑模型一样，其趋势与雷诺数相似，但流动阻力高出25%至40%。由于轻度锥度而测量到显著的压降，这可以通过动量考虑来估计，并且在较高的Dean数下，由于曲率效应发现了较小的压降增加。对于斑块模型，体内脉动流模拟的流动阻力比稳定流高出约10%，而对于光滑模型则未观察到差异。
