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胸腔镜与开胸手术治疗 Gross 分型 C 型食管闭锁的临床比较。

Clinical comparison between thoracoscopic and thoracotomy repair of Gross type C esophageal atresia.

机构信息

Department of Neonatal Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, 56 Nanlishi Road, Beijing, 100045, China.

Department of Neonatal Surgery, The Affiliated Children's Hospital of Nanchang University, Nanchang, 330006, China.

出版信息

BMC Surg. 2021 Nov 22;21(1):403. doi: 10.1186/s12893-021-01360-7.

Abstract

BACKGROUND

To compare the clinical outcomes between thoracoscopic approach and thoracotomy surgery in patients with Gross type C Esophageal atresia (EA) and tracheoesophageal fistula (TEF).

METHODS

Patients with Gross type C EA/TEF who underwent surgery from January 2007 to January 2020 at Beijing Children's Hospital were retrospectively analyzed. The patients were divided into two groups according to surgical approaches. The perioperative factors and postoperative complications were compared among the two groups.

RESULTS

One hundred and ninety patients (132 boys and 58 girls) with a median birth weight of 2975 (2600, 3200) g were included. The primary operations were performed via thoracoscopic (n = 62) and thoracotomy (n = 128) approach. After comparison of clinical characteristics between the two groups, we found that there were statistically significant differences in associated anomalies, method of fistula closure, duration of mechanical ventilation after surgery, feeding option before discharge, management of pneumothorax, and prognosis (all P < 0.05). To a certain extent, thoracoscopic surgery reduced the incidence of anastomotic leakage and increased the incidence of anastomotic stricture in this study. However, there were no statistically significant differences between the two groups in terms of operative time, postoperative pneumothorax, anastomotic leakage, anastomotic stricture, and recurrent tracheoesophageal fistula (all P > 0.05).

CONCLUSIONS

Thoracoscopy surgery for Gross type C EA/TEF is a safe and effective, minimally invasive technique with comparable operative time and incidence of postoperative complications.

摘要

背景

比较胸腔镜入路与开胸手术治疗 Gross 分型 C 型食管闭锁(EA)合并气管食管瘘(TEF)患儿的临床结局。

方法

回顾性分析 2007 年 1 月至 2020 年 1 月在北京儿童医院行手术治疗的 Gross 分型 C 型 EA/TEF 患儿,根据手术方式分为两组,比较两组患儿围手术期相关因素及术后并发症。

结果

共纳入 190 例患儿(男 132 例,女 58 例),中位出生体质量 2975(2600,3200)g。其中 62 例行胸腔镜手术,128 例行开胸手术。两组患儿临床特征比较,差异有统计学意义的项目包括合并畸形、瘘管闭合方式、术后机械通气时间、出院前喂养方式、气胸处理、预后(均 P<0.05)。胸腔镜手术在一定程度上降低了吻合口漏的发生率,增加了吻合口狭窄的发生率,但两组患儿手术时间、术后气胸、吻合口漏、吻合口狭窄、复发性气管食管瘘的发生率比较,差异均无统计学意义(均 P>0.05)。

结论

胸腔镜手术治疗 Gross 分型 C 型 EA/TEF 是一种安全有效的微创技术,具有可比较的手术时间和术后并发症发生率。

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