去功能化保护性造口可降低直肠癌患者低位前切除术后吻合口漏发生率。
Defunctioning Protective Stoma Can Reduce the Rate of Anastomotic Leakage after Low Anterior Resection in Rectal Cancer Patients.
作者信息
Lee Byoung Chul, Lim Seok-Byung, Lee Jong Lyul, Kim Chan Wook, Yoon Yong Sik, Park In Ja, Yu Chang Sik, Kim Jin Cheon
机构信息
Department of Surgery, Pusan National University Hospital, Busan, Korea.
Division of Colon and Rectal Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
出版信息
Ann Coloproctol. 2020 Jan 16. doi: 10.3393/ac.2019.11.19.1.
PURPOSE
This study aimed to identify risk factors for anastomotic leakage and to evaluate the impact of protective stoma on the rate of anastomotic leakage and subsequent management.
METHODS
This retrospective study analyzed data from 4,282 patients who underwent low anterior resection between 2007 and 2014. Among these, 1,367 (31.9%) underwent surgery to create protective diverting stoma and 232 (5.4%) experienced anastomotic leakage. At 6-month timepoints, data were evaluated to identify any correlation between the presence of diverting stoma and the incidence of anastomotic leakage. In addition, clinicopathological parameters were investigated to identify risk factors for anastomotic leakage.
RESULTS
Diverting stomas significantly reduced the rate of anastomotic leakage [HR 0.334, 95% CI 0.212.
目的
本研究旨在确定吻合口漏的危险因素，并评估保护性造口对吻合口漏发生率及后续处理的影响。
方法
这项回顾性研究分析了2007年至2014年间接受低位前切除术的4282例患者的数据。其中，1367例（31.9%）接受了保护性转流造口手术，232例（5.4%）发生了吻合口漏。在6个月的时间点，评估数据以确定转流造口的存在与吻合口漏发生率之间的任何相关性。此外，研究临床病理参数以确定吻合口漏的危险因素。
结果
转流造口显著降低了吻合口漏的发生率[风险比0.334，95%可信区间0.212。
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