Swiss Paraplegic Research, Nottwil, Switzerland.
Department of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Spinal Cord. 2020 May;58(5):570-580. doi: 10.1038/s41393-020-0428-4. Epub 2020 Feb 13.
Cross-sectional.
To examine the associations between activities, body structures and functions, and their relationship with aetiology, age and sex in persons with spinal cord injury (SCI) at discharge from first rehabilitation.
Swiss SCI Cohort Study (SwiSCI).
The study included 390 participants with newly acquired SCI and the International Classification of Functioning, Disability and Health (ICF) as conceptual frame of reference. Body structures were represented by injury level and severity; body functions by cardiovascular, pulmonary, skin, bowel and urinary functions and pain; mental functions by anxiety, depression, optimism and self-esteem; and activities by independence in performing activities of daily living (ADL). Using structural equation modelling (SEM), indirect effects of body structures and functions on independence in performing ADL through mental functions were tested for each mental function separately. For each structural model, fit was assessed using several indices and differences in aetiology, age and sex groups were explored.
The structural model about optimism showed good fit in all indices; the models about anxiety, depression and self-esteem showed conflicting fit indices, respectively. Within all models, effects on independence in performing ADL were mainly direct. Pain showed significant (P < 0.05) indirect effects on independence in performing ADL within the depression, optimism and self-esteem models. The model about anxiety showed differences in aetiology groups.
Using an ICF-based modelling approach, this study presents an attempt towards a more comprehensive understanding of functioning in first rehabilitation of persons with SCI, which might be fundamental for rehabilitation planning.
横断面研究。
探讨在首次康复出院时脊髓损伤(SCI)患者的活动、身体结构和功能之间的关联,及其与病因、年龄和性别的关系。
瑞士 SCI 队列研究(SwiSCI)。
本研究纳入了 390 名新发 SCI 患者,以国际功能、残疾和健康分类(ICF)作为概念参考框架。身体结构由损伤水平和严重程度表示;身体功能由心血管、肺部、皮肤、肠道和泌尿系统功能以及疼痛表示;心理功能由焦虑、抑郁、乐观和自尊表示;活动由日常生活活动(ADL)的独立性表示。使用结构方程模型(SEM),分别测试了心理功能对 ADL 独立性的身体结构和功能的间接影响。对于每个结构模型,使用多个指标评估了拟合度,并探讨了病因、年龄和性别组之间的差异。
关于乐观的结构模型在所有指标中均具有良好的拟合度;关于焦虑、抑郁和自尊的模型分别显示出相互矛盾的拟合指数。在所有模型中,对 ADL 独立性的影响主要是直接的。疼痛在抑郁、乐观和自尊模型中对 ADL 独立性有显著的(P<0.05)间接影响。关于焦虑的模型显示出病因组之间的差异。
本研究采用基于 ICF 的建模方法,试图更全面地了解 SCI 患者首次康复时的功能状况,这可能是康复计划的基础。