Ayouba Gamal, Lemonne François, Kombate Noufanangue Kanfitine, Bakriga Batarabadja, Yaovi Edem James, André-Pierre Max Uzel
Department of orthopaedics and traumatology, Comminuty Hospital of Kegue, Lome-Togo, P.O Box 81531, Togo.
Department of Orthopedic and Traumatology, Hôpital de Grasse, 06130, Grasse, France.
J Orthop. 2019 Dec 31;20:228-231. doi: 10.1016/j.jor.2019.12.014. eCollection 2020 Jul-Aug.
The Masquelet technique based on induced membrane is performed in two stages, first with generally an external fixator which is more and more relayed by an internal fixator. The aim of this study is to assess the results of stabilization by using intramedullary nailing from the first stage.
Nine patients were treated for a bone defect concerning 8 femurs and one tibia. The mean size of bone defect was 9.25 cm. It was secondary to a fracture (6 case) with bone defect and two septic and aseptic pseudarthrosis. In all cases the nailing was performed at the first stage of Masquelet. Prior to cement delivery, the site was thoroughly cleaned with iterative excisions as needed. Blood count control, normal CRP and negative culture were required before cement delivery. The cement was placed around the nail and encased the bony extremity. In the second stage, after removal of the cement, the defect was fulfilled by a mixture of cortico-cancellous autogenous graft taken from the iliac crest and phosphocalcic bone substitute. The nail was not changed in any patient. In post operative the mobilization of the above and underlying joints was immediate.
No sepsis was detected before the second time. Early weight bearing was allowed on average at the end of the 2 nd month. Total bearing without support was allowed at a mean of 5.5 months. All patients have consolidated. One patient had a shortening of 2.35 cm. The mean follow-up was 46.1 months. The average period to effective return to work was 21 months.
The nailing performed at the first stage of the induced membrane technique (IMT) gives good results. This modification does not seem to increase the risk of infection. These good results deserve to be confirmed by other studies to confirm the interests of associating nailing to IMT from the first stage.
基于诱导膜的Masquelet技术分两个阶段进行,首先通常使用外固定器,随后越来越多地由内固定器替代。本研究的目的是评估在第一阶段使用髓内钉固定的效果。
9例患者接受了骨缺损治疗,涉及8例股骨和1例胫骨。骨缺损的平均大小为9.25厘米。其继发于骨折(6例)合并骨缺损以及2例感染性和无菌性假关节。所有病例均在Masquelet技术的第一阶段进行髓内钉固定。在注入骨水泥之前,根据需要反复进行切除,彻底清理手术部位。在注入骨水泥之前,需要进行血常规检查、C反应蛋白正常以及培养阴性。将骨水泥放置在髓内钉周围并包裹骨端。在第二阶段,取出骨水泥后,用取自髂嵴的皮质松质自体骨移植混合物和磷酸钙骨替代物填充缺损。所有患者均未更换髓内钉。术后立即对上下关节进行活动。
第二次手术前未检测到感染。平均在第2个月末允许早期负重。平均在5.5个月时允许完全负重而无需支撑。所有患者均已骨愈合。1例患者缩短了2.35厘米。平均随访时间为46.1个月。有效恢复工作的平均时间为21个月。
在诱导膜技术(IMT)的第一阶段进行髓内钉固定效果良好。这种改良似乎并未增加感染风险。这些良好结果值得其他研究予以证实,以确认从第一阶段起将髓内钉固定与IMT相结合的益处。