Agunbiade Samiat, Nada Ayman, Bhimaniya Sudhir, Whitehead Matthew T, Mahdi Eman S
Department of Diagnostic Imaging and Radiology, University of Missouri Hospital/ Women's and Children's Hospital, Columbia, MO, USA.
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Radiol Case Rep. 2020 Feb 5;15(4):382-386. doi: 10.1016/j.radcr.2020.01.004. eCollection 2020 Apr.
Chordomas are rare, slow growing malignant tumors derived from notochord remnants that can arise anywhere along the neuronal axis. Chordomas are particularly rare in patients under 20 years of age and tend to be intracranial in location, as opposed to sacrococcygeal in adults. Metastasis at initial presentation is uncommon in all age groups and is exceedingly rare in the absence of local recurrence of the primary tumor. We report a case of advanced clival chordoma with marked nasopharyngeal disease extension and lung metastases at the time of presentation in a pediatric patient.
脊索瘤是一种罕见的、生长缓慢的恶性肿瘤，起源于脊索残余组织，可沿神经轴在任何部位发生。脊索瘤在20岁以下的患者中尤为罕见，且多位于颅内，与成人多发生于骶尾部的情况相反。在所有年龄组中，初诊时发生转移均不常见，而在原发性肿瘤无局部复发的情况下发生转移则极为罕见。我们报告一例小儿患者，初诊时为晚期斜坡脊索瘤，伴有明显的鼻咽部病变扩展及肺转移。
