一名耐药性局灶性肌阵挛发作患者接受丘脑底核单侧深部脑刺激的长期疗效
Long-term outcome of unilateral deep brain stimulation of the subthalamic nucleus for a patient with drug-resistant focal myoclonic seizure.
作者信息
Wang Xueyuan, Du Jialin, Wang Di, Xu Cuiping, Ren Zhiwei, Wang Yuping, Li Yongjie, Yu Tao, Ren Liankun
机构信息
Department of Functional Neurosurgery, Beijing Institute of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
Department of Neurology, Comprehensive Epilepsy Center of Beijing, Beijing Key Laboratory of Neuromodulation, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
出版信息
Ann Transl Med. 2020 Jan;8(1):18. doi: 10.21037/atm.2019.12.43.
It remains an unsolved problem in the treatment of patients with refractory focal epilepsy originating from the motor cortex since resection surgery can result in significant morbidity. Neurostimulation has emerged as an effective method for treating patients who are not suitable for conventional surgical procedures due to its relative safety, reversibility, and lower risk of complications. The subthalamic nucleus (STN) has been shown to be a potential target for treating refractory motor seizures. Here, we report a favorable outcome of unilateral deep brain stimulation (DBS) of the STN for a patient with drug-resistant focal myoclonic seizures during a 5-year follow-up period.
对于起源于运动皮层的难治性局灶性癫痫患者的治疗，这仍然是一个未解决的问题，因为切除手术可能会导致严重的发病率。神经刺激因其相对安全性、可逆性和较低的并发症风险，已成为治疗不适合传统手术的患者的有效方法。丘脑底核（STN）已被证明是治疗难治性运动性癫痫发作的潜在靶点。在此，我们报告了一名药物难治性局灶性肌阵挛性癫痫患者在5年随访期间接受STN单侧深部脑刺激（DBS）的良好结果。
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