Underwood Patrick W, Gerber Michael H, Hughes Steven J
Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
Ann Pancreat Cancer. 2019 Jan;2. doi: 10.21037/apc.2018.12.02. Epub 2019 Jan 16.
Minimally invasive approaches to abdominal surgical procedures have provided superior outcomes when compared to the open approach and thus have become the standard of care. However, minimally invasive pancreatoduodenectomy (MIPD) presents unique difficulties for both laparoscopic and robotic platforms and remains controversial. Ongoing concerns continue about the minimally invasive approach creating meaningful benefit when system-wide data may suggest MIPD results in increased morbidity and mortality during the learning curve. This treatise explores the current state of MIPD, reviewing the volume and quality of data that supports benefit while contrasting the benefits to the unique challenges associated with MIPD that may lead to unacceptable rates of complications and death. We conclude that in a handful of centers, MIPD confers an iterative but not transformative benefit. Significant barriers to the wide-spread acceptance of MIPD are apparent and persist, including: lack of high level data confirming clinical benefit, well defined patient selection criteria, formal education programs that address challenges of the learning curve, and ultimately value.
与开放手术相比,腹部外科手术的微创方法已取得了更好的治疗效果,因此已成为标准治疗方式。然而,微创胰十二指肠切除术(MIPD)在腹腔镜和机器人手术平台上都存在独特的困难,并且仍然存在争议。当全系统数据可能表明MIPD在学习曲线期间会导致发病率和死亡率增加时,人们对微创方法是否能产生有意义的益处一直存在担忧。本论文探讨了MIPD的当前状况,回顾了支持其益处的数据量和质量,同时将这些益处与MIPD相关的独特挑战进行对比,这些挑战可能导致不可接受的并发症和死亡率。我们得出结论,在少数几个中心,MIPD带来了渐进但并非变革性的益处。MIPD广泛被接受存在明显且持续的重大障碍,包括:缺乏确认临床益处的高级别数据、明确的患者选择标准、应对学习曲线挑战的正规教育项目以及最终的价值。