Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
J Vet Intern Med. 2020 Mar;34(2):1018-1027. doi: 10.1111/jvim.15726. Epub 2020 Feb 14.
Abomasitis is a syndrome affecting young milk-fed calves. The current veterinary literature describes mainly its necropsy findings.
To describe the clinical presentation, complementary tests, treatments, and case-fatality rate of calves with a clinical diagnosis of abomasitis and to identify potential factors associated with outcome.
Observational retrospective cohort study (2006-2016). Review of the medical records of calves <3 months of age presented with abdominal and abomasal distension for <7 days that were clinically diagnosed with abomasitis at the Faculty of Veterinary Medicine of the Université de Montréal. A follow-up examination was conducted by telephone interview.
Twenty-three calves clinically diagnosed with abomasitis.
Median age of presentation was 3 days (range, 0-62 days). The typical duration of the clinical course was <24 hours (15/23). On admission, the 2 most common clinical signs were anorexia (13/14) and positive succussion (13/14). Hyper-l-lactatemia (15/16) and increased γ-glutamyl-transferase activity (13/14) were the most common laboratory abnormalities. Hypoproteinemia (19/22) and a left shift (15/18) of the neutrophils also were observed. The short-term case-fatality rate was 52% (12/23). The clinical diagnosis was confirmed on all necropsied calves. Clostridium spp. and Escherichia coli were the most frequently isolated bacteria. Based on univariate statistical analysis, the surviving calves were significantly (P < .05) less hypothermic, less acidemic, less hyper-l-lactatemic, and had lower serum creatinine concentrations on admission than did the deceased calves.
In our study, abomasitis was associated with a guarded prognosis.
真胃炎是一种影响年轻哺乳犊牛的综合征。目前兽医文献主要描述了其剖检发现。
描述临床诊断为真胃炎的犊牛的临床表现、辅助检查、治疗方法和病死率，并确定与结果相关的潜在因素。
观察性回顾性队列研究（2006-2016 年）。对在蒙特利尔大学兽医学院就诊的<3 月龄、腹部和真胃膨胀<7 天且临床诊断为真胃炎的犊牛的病历进行回顾。通过电话访谈进行随访检查。
23 头临床诊断为真胃炎的犊牛。
就诊时的中位年龄为 3 日龄（范围 0-62 日龄）。典型的临床病程持续时间<24 小时（15/23）。入院时，最常见的 2 个临床症状是厌食（13/14）和阳性震水音（13/14）。最常见的实验室异常为高 l-乳酸血症（15/16）和γ-谷氨酰转移酶活性升高（13/14）。也观察到低蛋白血症（19/22）和中性粒细胞左移（15/18）。短期病死率为 52%（12/23）。所有剖检犊牛均证实了临床诊断。最常分离到的细菌为梭菌属和大肠杆菌。基于单变量统计分析，存活犊牛入院时体温较低、酸中毒较轻、高 l-乳酸血症较轻、血清肌酐浓度较低，与死亡犊牛相比差异有统计学意义（P<0.05）。
在本研究中，真胃炎的预后较差。
