Roeder B L, Chengappa M M, Nagaraja T G, Avery T B, Kennedy G A
J Am Vet Med Assoc. 1987 Jun 15;190(12):1550-5.
Eight neonatal calves (2 to 21 days old) with suspected abomasal displacement or intestinal obstruction after acute onset of abdominal tympany, colic, depression, or death were referred to Kansas State University for clinical examination or for necropsy. Results of routine hematologic and serum chemical analyses did not reveal consistent changes. Necropsy revealed abomasal distention, with various degrees of abomasitis, hemorrhage, and ulceration, but did not reveal evidence of displaced abomasum or obstructed intestine. Specimens of ruminal contents collected via stomach tube or at necropsy and abomasal contents collected at necropsy were obtained for anaerobic bacteriologic culture. Clostridium perfringens was isolated from all specimens, and on the basis of toxin neutralization tests in mice, 7 were type A and one was type E. Copper concentrations in serum and tissues were within normal limits. It appeared that the acute abdominal syndrome in these neonatal calves was unrelated to copper deficiency, and that C perfringens, particularly type A, may have had an appreciable contributory role in its pathogenesis.
8头新生犊牛（2至21日龄）在急性出现腹部鼓胀、绞痛、抑郁或死亡后，疑似发生皱胃移位或肠梗阻，被转诊至堪萨斯州立大学进行临床检查或尸检。常规血液学和血清化学分析结果未显示出一致的变化。尸检发现皱胃扩张，伴有不同程度的皱胃炎、出血和溃疡，但未发现皱胃移位或肠道梗阻的证据。通过胃管采集的瘤胃内容物样本或尸检时采集的样本，以及尸检时采集的皱胃内容物样本，用于厌氧细菌培养。从所有样本中均分离出产气荚膜梭菌，根据小鼠毒素中和试验，7株为A型，1株为E型。血清和组织中的铜浓度在正常范围内。这些新生犊牛的急性腹部综合征似乎与铜缺乏无关，产气荚膜梭菌，尤其是A型，可能在其发病机制中起到了相当大的作用。
