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创伤性胰十二指肠切除术:一期还是二期?

Pancreaticodudonectomy in trauma: One or two stages?

作者信息

de Carvalho Maria Eduarda Alonso Joaquim, Cunha André Gusmão

机构信息

Member of Trauma and Emergency Research Group, Salvador, Brazil; School of Medicine, Federal University of Bahia, Salvador, Brazil.

Member of Trauma and Emergency Research Group, Salvador, Brazil; Department of Surgery, Federal University of Bahia, Salvador, Brazil.

出版信息

Injury. 2020 Mar;51(3):592-596. doi: 10.1016/j.injury.2020.01.018. Epub 2020 Jan 24.

Abstract

INTRODUCTION

Duodenopancreatic trauma is rare and presents high morbidity and mortality rates. Pancreaticoduodenectomy (PD) is the only possible treatment indicated for the most complex injuries (grades IV and V). Although, it is commonly a one-stage procedure, damage control surgery corroborates with a two-stage PD performed on unstable trauma victims.

OBJECTIVES

Compare the mortality rate of one and two-stage PD in trauma patients.

MATERIALS AND METHODS

A systematic electronic search of PubMed, Elsevier, LILACS, Scielo, and Capes was conducted on all studies written in English, Portuguese and Spanish with no restriction to publication dates. Review articles, case reports, editorials, animal studies, pediatric and non-trauma scenarios were excluded.

RESULTS

We selected twenty-two publications, with a total of 149 duodenopancreatic trauma victims who underwent PD, with an overall mortality rate of 42 patients (28.2%). Two-stage PD was exclusively performed on unstable patients (N = 31) with a mortality rate of 38.7%. In a sample of 79 patients submitted to a one-stage PD, 38 patients (48.1%) were unstable with a mortality rate of 34.2%. One-stage PD for stable patients had a mortality rate of 14.6% DISCUSSION: Since 1983, hemodynamic state impacts on surgery methods and strategies for trauma patients. Prior to that, one stage PD was not restricted to stable patients.

CONCLUSION

There were no differences in mortality rates when comparing two and one-stage PD in hemodynamic unstable patients, who had duodenopancreatic lesions (grades IV or V).

摘要

引言

十二指肠胰腺创伤较为罕见,发病率和死亡率都很高。胰十二指肠切除术(PD)是针对最复杂损伤(IV级和V级)的唯一可行治疗方法。虽然通常是一期手术,但损伤控制手术支持对不稳定创伤患者进行两期PD手术。

目的

比较创伤患者一期和两期PD手术的死亡率。

材料与方法

对PubMed、爱思唯尔、LILACS、Scielo和Capes进行系统的电子检索,检索所有用英文、葡萄牙文和西班牙文撰写的研究,不限制出版日期。排除综述文章、病例报告、社论、动物研究、儿科和非创伤情况。

结果

我们筛选出22篇出版物,共有149例接受PD手术的十二指肠胰腺创伤患者,总死亡率为42例(28.2%)。两期PD手术仅用于不稳定患者(N = 31),死亡率为38.7%。在79例行一期PD手术的患者样本中,38例(48.1%)为不稳定患者,死亡率为34.2%。稳定患者行一期PD手术的死亡率为14.6%。讨论:自1983年以来,血流动力学状态影响创伤患者的手术方法和策略。在此之前,一期PD手术并不局限于稳定患者。

结论

对于有十二指肠胰腺损伤(IV级或V级)的血流动力学不稳定患者,比较两期和一期PD手术的死亡率没有差异。

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