Risk Sciences International, 251 Laurier Avenue West, Suite 700, Ottawa, ON, Canada.
Risk Sciences International, 251 Laurier Avenue West, Suite 700, Ottawa, ON, Canada; McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, ON, Canada.
Neurotoxicology. 2021 Mar;83:186-198. doi: 10.1016/j.neuro.2020.01.010. Epub 2020 Feb 10.
New European legislation known as REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) was introduced in 2007 to increase the speed at which the health and/or environmental risks of industrial chemicals were being assessed and managed (REACH (EC) No 1907/2006). REACH consolidated earlier chemicals-control statutes and placed the burden of assessing, and identifying the means to manage risks on industry. This paper details the REACH process for controlling and managing hazardous chemicals and challenges encountered in applying the provisions of REACH and the guidance documents available from European Chemical Agency. Special attention is paid to challenges in evaluating potential health risks of metals such as aluminum and aluminum compounds. Lessons learned from over a decade of experience with REACH legislation are also noted.
新的欧洲法规称为 REACH（化学品注册、评估、授权和限制）于 2007 年推出，旨在加快评估和管理工业化学品的健康和/或环境风险的速度（REACH（EC）No 1907/2006）。REACH 整合了早期的化学品控制法规，并将评估和确定管理风险的方法的负担放在了工业界身上。本文详细介绍了控制和管理危险化学品的 REACH 流程，以及在应用 REACH 规定和欧洲化学品管理局提供的指导文件时遇到的挑战。特别关注评估金属（如铝和铝化合物）潜在健康风险的挑战。还注意到了从 REACH 立法十多年的经验中吸取的教训。
