Yunitri Ninik, Kao Ching-Chiu, Chu Hsin, Voss Joachim, Chiu Huei-Ling, Liu Doresses, Shen Shu-Tai H, Chang Pi-Chen, Kang Xiao Linda, Chou Kuei-Ru
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; Mental Health and Psychiatric Nursing Department, Faculty of Nursing, Muhammadiyah University of Jakarta, Indonesia.
School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; Department of Nursing, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
J Psychiatr Res. 2020 Apr;123:102-113. doi: 10.1016/j.jpsychires.2020.01.005. Epub 2020 Jan 28.
Eye Movement Desensitization and Reprocessing (EMDR) has been well established as an effective treatment for post-traumatic stress disorder (PTSD). However, PTSD has been re-categorized as part of trauma and stressor-related disorders instead of anxiety disorders. We conducted the first meta-analysis on Randomized Controlled Trials to evaluate the effectiveness of EMDR on reducing symptoms of anxiety disorders.
A manual and systematic search using various databases and reference lists of systematic review articles published up to December 2018 was conducted. The symptoms of anxiety, phobia, panic, traumatic feelings and behaviors/somatic symptoms were examined. Hedges' g effect sizes were computed, and random effect models were used for all analyses.
A total of 17 trials with 647 participants were included in this meta-analysis. EMDR was associated with a significant reduction of anxiety (g = -0.71; 95% CI: -0.96 to -0.47), panic (g = -0.62; 95% CI: -1.10 to -0.14), phobia (g = -0.45; 95% CI: -0.81 to -0.08), behavioural/somatic symptoms (g = -0.40; 95% CI: -0.63 to -0.12), but not traumatic feelings (g = -0.48; 95% CI: -1.14 to -0.18). Subgroup analysis revealed greater effects of EMDR if compared to passive control. However, the effects were not significantly different based on the duration, number of therapy sessions, or the number of weekly sessions.
Our meta-analysis indicates that EMDR is efficacious for reducing symptoms of anxiety, panic, phobia, and behavioural/somatic symptoms. Further research is needed to explore EMDR's long term efficacy on anxiety disorders.
眼动脱敏再处理疗法（EMDR）已被确认为治疗创伤后应激障碍（PTSD）的有效方法。然而，PTSD已被重新归类为创伤及应激相关障碍的一部分，而非焦虑症。我们进行了首次关于随机对照试验的荟萃分析，以评估EMDR减轻焦虑症症状的有效性。
使用各种数据库及截至2018年12月发表的系统评价文章的参考文献列表进行人工和系统检索。对焦虑、恐惧、惊恐、创伤性情感及行为/躯体症状进行检查。计算Hedges' g效应量，并对所有分析采用随机效应模型。
本荟萃分析共纳入17项试验，647名参与者。EMDR与焦虑（g = -0.71；95%CI：-0.96至-0.47）、惊恐（g = -0.62；95%CI：-1.10至-0.14）、恐惧（g = -0.45；95%CI：-0.81至-0.08）、行为/躯体症状（g = -0.40；95%CI：-0.63至-0.12）的显著减轻相关，但与创伤性情感（g = -0.48；95%CI：-1.14至-0.18）无关。亚组分析显示，与被动对照相比，EMDR的效果更佳。然而，基于治疗时长、治疗次数或每周治疗次数，效果并无显著差异。
我们的荟萃分析表明，EMDR在减轻焦虑、惊恐、恐惧及行为/躯体症状方面有效。需要进一步研究以探索EMDR对焦虑症的长期疗效。
