Chen Ying-Ren, Hung Kuo-Wei, Tsai Jui-Chen, Chu Hsin, Chung Min-Huey, Chen Su-Ru, Liao Yuan-Mei, Ou Keng-Liang, Chang Yue-Cune, Chou Kuei-Ru
Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan, and Taoyuan Armed Forces General Hospital, Longtan, Taiwan.
Division of Neurology, Department of Internal Medicine, Yuan's General Hospital, Kaohsiung, Taiwan.
PLoS One. 2014 Aug 7;9(8):e103676. doi: 10.1371/journal.pone.0103676. eCollection 2014.
We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades.
We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome.
The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients.
This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.
我们通过调查眼动脱敏再处理（EMDR）疗法对过去20年中接受治疗的创伤后应激障碍（PTSD）患者的创伤后应激障碍症状、抑郁、焦虑和主观痛苦的影响，进行了首次临床研究的荟萃分析。
我们对1991年至2013年间发表的26项关于EMDR疗法治疗PTSD的随机对照试验结果进行了定量荟萃分析，这些试验通过ISI科学网、Embase、考克兰图书馆、MEDLINE、PubMed、Scopus、PsycINFO以及护理与联合健康文献累积索引电子数据库确定，其中分别有22项、20项、16项和11项研究将EMDR对PTSD症状、抑郁、焦虑和主观痛苦的影响作为主要临床结局进行评估。
荟萃分析显示，EMDR治疗显著减轻了PTSD患者的PTSD症状（g = -0.662；95%置信区间（CI）：-0.887至-0.436）、抑郁（g = -0.643；95%CI：-0.864至-0.422）、焦虑（g = -0.640；95%CI：-0.890至-0.390）和主观痛苦（g = -0.956；95%CI：-1.388至-0.525）。
本研究证实，EMDR疗法显著减轻了PTSD患者的PTSD症状、抑郁、焦虑和主观痛苦。亚组分析表明，每次治疗时长超过60分钟是改善焦虑和抑郁的主要因素，而有PTSD团体治疗经验的治疗师是减轻PTSD症状的主要因素。
