Textile Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Textile Engineering Department, Amirkabir University of Technology, Tehran, Iran.
Carbohydr Polym. 2020 Apr 1;233:115873. doi: 10.1016/j.carbpol.2020.115873. Epub 2020 Jan 15.
In this research, cellulose nanocrystal (CNC) was synthesized from cotton waste using controlled hydrolysis against 64 % (w/w) sulfuric acid solution. The produced nanoparticles were then characterized using FTIR, XRD, TGA, and DLS analyses. Biaxial electrospinning technique was used to produce CNC incorporated PCL-PVA/NaAlg nanofibers. The sodium alginate portion was then crosslinked via submerging the samples in calcium chloride aqueous solution. The CNC incorporated and crosslinked sample was characterized using SEM, FTIR, and TGA techniques. Results confirmed the presence of CNC nanoparticles and alginate crosslinking reaction. Mechanical studies showed that CNC incorporation increases the tensile modulus by 65 %. Also, the crosslinked samples exhibited an increase in elongation at break. Water contact angle studies suggested that CNC incorporation and crosslinking improves nanofiber hydrophilicity. Cell viability of more than 90 % was observed in CNC incorporated PCL-CaAlg nanofibers. Also, SEM images of cells on nanofiber scaffolds showed better cell growth and attachment in PCL-CaAlg-CNC samples.
在这项研究中，使用 64%（w/w）硫酸溶液对棉废料进行控制水解，合成了纤维素纳米晶（CNC）。然后使用傅里叶变换红外光谱（FTIR）、X 射线衍射（XRD）、热重分析（TGA）和动态光散射（DLS）分析对所制备的纳米颗粒进行了表征。采用双轴静电纺丝技术制备了包含 CNC 的 PCL-PVA/NaAlg 纳米纤维。然后通过将样品浸入氯化钙水溶液中来使部分海藻酸钠交联。使用扫描电子显微镜（SEM）、傅里叶变换红外光谱（FTIR）和热重分析（TGA）技术对 CNC 掺入和交联的样品进行了表征。结果证实了 CNC 纳米颗粒的存在和海藻酸钠的交联反应。力学研究表明，CNC 的掺入可使拉伸模量提高 65%。此外，交联样品的断裂伸长率也有所提高。水接触角研究表明，CNC 的掺入和交联可提高纳米纤维的亲水性。在含有 CNC 的 PCL-CaAlg 纳米纤维中观察到超过 90%的细胞活力。此外，在纳米纤维支架上细胞的 SEM 图像显示，在 PCL-CaAlg-CNC 样品中细胞生长和附着情况更好。
