New Mexico Clinical Research & Osteoporosis Center, 300 Oak Street NE, Albuquerque, NM, 87106, USA.
Optum, 11000 Optum Circle, Eden Prairie, MN, 55344, USA.
Osteoporos Int. 2020 Jul;31(7):1299-1304. doi: 10.1007/s00198-020-05334-y. Epub 2020 Feb 15.
This study expands on previous findings that hip fracture rates may no longer be declining. We found that age- and sex-adjusted fracture rates in the US plateaued or increased through mid-2017 in a population of commercially insured and Medicare Advantage health plan enrollees, in contrast to a decline from 2007 to 2013.
The purpose of this study was to evaluate fracture trends in US commercial and Medicare Advantage health plan members aged ≥ 50 years between 2007 and 2017.
Retrospective analysis of the Optum Research Database from January 1, 2007, to May 31, 2017.
Of 1,841,263 patients identified with an index fracture, 930,690 were case-qualifying and included in this analysis. The overall age- and sex-adjusted fracture rate decreased from 14.67/1000 person-years (py) in 2007 to 11.79/1000 py in 2013, followed by a plateau for the next 3 years and then an increase to 12.50/1000 py in mid-2017. In females aged ≥ 65 years, fracture rates declined from 27.49/1000 py in 2007 to 22.08/1000 py in 2013, then increased to 24.92/1000 py in mid-2017. Likewise, fracture rates in males aged ≥ 65 years declined from 2007 (12.00/1000 py) to 2013 (10.72/1000 py), then increased to 12.04/1000 py in mid-2017. The age- and sex-adjusted fracture rates for most fracture sites declined from 2007 to 2013 by 3.7% per year (P = 0.310).
Following a consistent decline in fracture rate from 2007 to 2013, trends from 2014 to 2017 indicate fracture rates are no longer declining and, for some fracture types, rates are rising.
本研究旨在评估 2007 年至 2017 年期间美国商业和医疗保险优势健康计划中≥50 岁成员的骨折趋势。
对 2007 年 1 月 1 日至 2017 年 5 月 31 日期间 Optum Research Database 的回顾性分析。
在 1841263 名患有索引骨折的患者中,有 930690 名符合病例纳入标准并纳入本分析。总体年龄和性别调整后的骨折率从 2007 年的 14.67/1000 人年(py)降至 2013 年的 11.79/1000 py,随后在接下来的 3 年中保持稳定,然后在 2017 年中期上升至 12.50/1000 py。在≥65 岁的女性中,骨折率从 2007 年的 27.49/1000 py 降至 2013 年的 22.08/1000 py,然后在 2017 年中期上升至 24.92/1000 py。同样,≥65 岁的男性骨折率从 2007 年(12.00/1000 py)降至 2013 年(10.72/1000 py),然后在 2017 年中期上升至 12.04/1000 py。大多数骨折部位的年龄和性别调整骨折率从 2007 年至 2013 年每年下降 3.7%(P=0.310)。
在 2007 年至 2013 年骨折率持续下降之后,2014 年至 2017 年的趋势表明骨折率不再下降,并且对于某些骨折类型,骨折率正在上升。