Department of Research & Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 100 Los Robles, 2nd Floor, Pasadena, CA 91101, USA.
Osteoporos Int. 2013 Jan;24(1):373-6. doi: 10.1007/s00198-012-1938-5. Epub 2012 Feb 21.
Hip fractures are a large public health problem with significant negative impact on an individual's overall health and survival. But while the total numbers of persons affected by hip fractures may be anticipated to increase, incidence rates appear to be declining.
To describe annual hip fracture incidence rate trends in an integrated health-care organization over 1997-2006, during which a proactive bone health program was initiated program-wide and other secular trends occurred in the population.
For this ecologic trend study, we identified all men and women ≥45 years old as of January 1 of each year. Incident fractures for each year were identified using ICD-9 diagnosis codes 820-820.9, excluding all subjects who had fractures in prior years. Annual person-time at risk for hip fracture was determined from enrollment data. Sex- and age-specific and adjusted annual incidence rates were calculated.
The overall annual hip fracture incidence rate for men declined from 1.52/1,000 person-years in 1997 to 1.29/1,000 person-years in 2006, a 15.3% (95% confidence interval [CI]=6.2-24.5) decrease. For women, incidence declined from 2.65/1,000 person-years in 1997 to 2.24/1,000 person-years in 2006, a 15.3% (95% CI=8.7-21.9) decrease. Among subjects aged 85 years or older, incidence rates for men declined from 27.0/1,000 to 18.9/1,000 person-years, and for women they declined from 32.7/1,000 to 27.1/1,000 person-years.
Hip fracture incidence has been declining in all age groups over the past 10 years. While many factors may contribute to this decline, the results are consistent with a potential benefit of the active bone health intervention.
描述 1997 年至 2006 年期间一个综合医疗保健机构中髋部骨折的年发生率趋势,在此期间,在全组织范围内启动了一项积极的骨骼健康计划,并且人群中还出现了其他的长期趋势。
本生态趋势研究确定了每年 1 月 1 日年满 45 岁及以上的所有男性和女性。每年的骨折病例通过 ICD-9 诊断代码 820-820.9 确定,不包括所有在前几年发生过骨折的患者。通过登记数据确定髋部骨折的每年个体风险时间。计算性别和年龄特定的调整后年发生率。
男性的总体髋部骨折年发生率从 1997 年的 1.52/1000 人年降至 2006 年的 1.29/1000 人年,下降了 15.3%(95%置信区间[CI]:6.2-24.5)。对于女性,发生率从 1997 年的 2.65/1000 人年降至 2006 年的 2.24/1000 人年,下降了 15.3%(95%置信区间[CI]:8.7-21.9)。在 85 岁及以上的患者中,男性的发病率从 27.0/1000 人年降至 18.9/1000 人年,女性的发病率从 32.7/1000 人年降至 27.1/1000 人年。
在过去的 10 年中,所有年龄段的髋部骨折发生率都在下降。虽然许多因素可能导致这种下降,但结果与积极的骨骼健康干预的潜在益处一致。