Narla Radhika R, Adler Robert A
Division of Endocrinology, Metabolism, and Nutrition, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.
Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.
Osteoporos Int. 2025 Feb;36(2):163-166. doi: 10.1007/s00198-024-07337-5. Epub 2024 Dec 13.
The US Preventive Services Task Force has not recommended osteoporosis screening in men. Department of Veterans Affairs clinicians reviewed the literature on male osteoporosis screening and treatment. They concluded that targeted screening identifies men at risk and osteoporosis drugs reduce fracture risk similarly in men and women.
PURPOSE/INTRODUCTION: The US Preventive Services Task Force (USPSTF) has found insufficient evidence for recommending for or against osteoporosis screening in men. Department of Veterans Affairs osteoporosis experts reviewed the literature on osteoporosis screening and treatment in men.
Although not done systematically, the literature was reviewed by a panel of 20 Department of Veterans Affairs clinicians with extensive experience with osteoporosis in men. Virtual meetings and multiple email communications resulted in a consensus.
Screening, particularly targeted screening in men, has been found to identify men at risk for fracture. Prior studies have shown osteoporosis drugs have similar effects in men and women. A recent large observational trial demonstrated that hip fracture risk is similarly reduced for both sexes by current medications.
The consensus of the panel was that targeted screening of men for osteoporosis would lead to greater use of osteoporosis medication, lowering fracture risk.
美国预防服务工作组未建议对男性进行骨质疏松症筛查。退伍军人事务部的临床医生回顾了有关男性骨质疏松症筛查和治疗的文献。他们得出结论，针对性筛查可识别出有风险的男性，并且骨质疏松症药物在男性和女性中降低骨折风险的效果相似。
目的/引言：美国预防服务工作组（USPSTF）发现，对于建议或反对对男性进行骨质疏松症筛查，证据不足。退伍军人事务部的骨质疏松症专家回顾了有关男性骨质疏松症筛查和治疗的文献。
尽管未进行系统的文献回顾，但由20名在男性骨质疏松症方面有丰富经验的退伍军人事务部临床医生组成的小组进行了回顾。通过虚拟会议和多次电子邮件交流达成了共识。
已发现筛查，特别是对男性的针对性筛查，能够识别出有骨折风险的男性。先前的研究表明，骨质疏松症药物在男性和女性中具有相似的效果。最近一项大型观察性试验表明，当前药物对男女髋部骨折风险的降低效果相似。
该小组的共识是，对男性进行骨质疏松症针对性筛查将导致更多地使用骨质疏松症药物，从而降低骨折风险。
