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为什么并非总能取出非必需的下腔静脉滤器?瑞士一所三级护理大学医院 19 年的真实世界经验。

Why optional inferior vena cava filters are not always retrieved? A real world 19 years experience in a Swiss tertiary care university hospital.

机构信息

Angiology Division, CHUV University Hospital, Lausanne, Switzerland.

Department of Radiology, CHUV University Hospital, Lausanne, Switzerland.

出版信息

Eur J Intern Med. 2020 Jun;76:64-70. doi: 10.1016/j.ejim.2020.01.025. Epub 2020 Feb 13.

DOI:10.1016/j.ejim.2020.01.025
PMID:32063490
Abstract

BACKGROUND

inferior vena cava filters (IVCF) are widely used to prevent thromboembolic events in patients not suitable for anticoagulation (AC). Although new generations of filters are optional and therefore retrievable, most of them become permanent. Aim of our study was to evaluate real life IVCF management in a tertiary hospital including retrieval rates and reasons for permanent filtering.

MATERIALS AND METHODS

Electronic charts from patients receiving IVCF in a Swiss university hospital, during 1999-2017, were retrospectively identified. Patients were classified in two groups, according to filter retrieval (RG) or not (NRG). Type and reasons of filter placement were assessed. Retrieval, complications, and mortality rates were calculated. Reasons of non-retrieval were analyzed.

RESULTS

920 patients received an IVCF during 1999-2017. Filters were retrieved in 372 patients (40.65%). Subjects in the NRG were significantly older, more chronically ill, and presented higher mortality rate at 12 months following filter insertion (29.60% vs. 4.30%; p < 0.001). Reasons for non-retrieval included lack of follow-up (22.34%), persistent contraindications to AC (20.51%), technical issues (17.40%), and severe morbidity with short life expectancy (17.22%). Overall, complication rates after filter placement was 18.58%. Most reported complication was filter thrombosis (15.60%).

CONCLUSIONS

In a real life setting, optional IVCF are still too often left in place indefinitely. Need for a systematic follow-up to ensure prompt filter retrieval is warranted. IVCF are not retrieved mostly in chronically and more severely ill patients, likely accounting for higher mortality in these subjects.

摘要

背景

下腔静脉滤器(IVCF)广泛用于预防不适合抗凝(AC)治疗的患者发生血栓栓塞事件。尽管新一代滤器是可选的,因此可以回收,但大多数滤器会成为永久性的。我们研究的目的是评估在一家三级医院中 IVCF 的实际管理情况,包括回收率和永久性过滤的原因。

材料和方法

回顾性地确定了 1999 年至 2017 年期间在瑞士大学医院接受 IVCF 的患者的电子病历。根据滤器是否回收(RG)将患者分为两组。评估了滤器放置的类型和原因。计算了回收、并发症和死亡率。分析了未回收的原因。

结果

1999 年至 2017 年期间,920 名患者接受了 IVCF。372 名患者(40.65%)回收了滤器。NRG 组的患者年龄明显更大,慢性病更多,并且在滤器插入后 12 个月的死亡率更高(29.60%比 4.30%;p<0.001)。未回收的原因包括缺乏随访(22.34%)、持续存在抗凝禁忌(20.51%)、技术问题(17.40%)和严重的发病率及预期寿命较短(17.22%)。总的来说,滤器放置后的并发症发生率为 18.58%。最常见的并发症是滤器血栓形成(15.60%)。

结论

在实际环境中,仍有许多可选的 IVCF 被永久放置。需要进行系统的随访,以确保及时回收滤器。IVCF 未被回收的主要原因是慢性和严重疾病患者,这可能导致这些患者的死亡率更高。

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