Takami Yasukage, Aga Fumitoshi, Mitamura Katsuya, Norikane Takashi, Okuda Hanae, Yamamoto Yuka, Miyake Minoru, Nishiyama Yoshihiro
Department of Radiology, Faculty of Medicine, Kagawa University, Japan.
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University, Japan.
Asia Ocean J Nucl Med Biol. 2020 Winter;8(1):84-87. doi: 10.22038/aojnmb.2019.13876.
Ewing Sarcoma is the second most common type of bone cancer in children. The dominant features of this malignant bone tumor are the tendency for rapid growth and metastasis. In addition, Ewing sarcoma of the mandible is extremely rare and can be mistaken for odontogenic infection. We report a 14-year-old girl who had had swelling, pain, and hypoesthesia in the left cheek for three weeks. She was diagnosed with pericoronitis initially, and then referred toour hospital due to worsening symptoms. CT and MRI revealed an expanding and destructive mass mainly in the left mandible. F-fluorodeoxyglucose (F-FDG) positron emission tomography (PET) and fused PET/CT demonstratedincreased uptake in the mandibular lesion. Whole-body F-FDG PET images showed no abnormal activity except for the mandibular lesion. Histologic examination confirmed Ewing sarcoma. Although this tumor has an aggressive clinical behavior and rapid growth, early diagnosis can reduce patient's morbidity, mortality and thus it is important to distinguish it from periodontal inflammation.
尤因肉瘤是儿童第二常见的骨癌类型。这种恶性骨肿瘤的主要特征是生长迅速且有转移倾向。此外，下颌骨尤因肉瘤极为罕见，可能被误诊为牙源性感染。我们报告一名14岁女孩，她左侧脸颊肿胀、疼痛和感觉减退已有三周。最初她被诊断为冠周炎，后因症状加重转诊至我院。CT和MRI显示主要位于左下颌骨的一个不断扩大且具有破坏性的肿块。F-氟脱氧葡萄糖（F-FDG）正电子发射断层扫描（PET）及PET/CT融合显像显示下颌骨病变处摄取增加。全身F-FDG PET图像显示除下颌骨病变外无异常活动。组织学检查确诊为尤因肉瘤。尽管这种肿瘤具有侵袭性临床行为且生长迅速，但早期诊断可降低患者的发病率和死亡率，因此将其与牙周炎症相鉴别很重要。
