Bachmaier Samuel, DiFelice Gregory S, Sonnery-Cottet Bertrand, Douoguih Wiemi A, Smith Patrick A, Pace Lee J, Ritter Daniel, Wijdicks Coen A
Department of Orthopedic Research, Arthrex, Munich, Germany.
Hospital for Special Surgery, New York, New York, USA.
Orthop J Sports Med. 2020 Jan 29;8(1):2325967119897421. doi: 10.1177/2325967119897421. eCollection 2020 Jan.
Recently, there has been a resurgence of interest in primary repair of the anterior cruciate ligament (ACL), with fixation techniques evolving. However, to date, there have been no biomechanical studies comparing fixed to adjustable fixation repair techniques.
Adjustable ACL repair provides for improved stabilization compared with fixed techniques with respect to both gap formation and residual load-bearing capability.
Controlled laboratory study.
A total of 4 different ACL repair techniques (n = 5 per group), including single- and double-cinch loop (CL) cortical button fixation as well as knotless single-suture anchor fixation, were tested using a porcine model. For adjustable single-CL loop fixation, additional preconditioning (10 cycles at 0.5 Hz) was performed. The force after fixation and the actuator displacement to achieve a time-zero preload of 10 N were measured for fixed techniques. Incrementally increasing cycling (1 mm/500 cycles) from 1 to 8 mm was performed for 4000 cycles at 0.75 Hz before pull to failure (50 mm/min). The final residual peak load and gap formation for each test block were analyzed as well as ultimate strength.
Knot tying of a single-CL over a button (mean ± SD, 0.66 ± 0.23 mm) and knotless anchor fixation (0.20 ± 0.12 mm) resulted in significant time-zero gaps ( < .001) and significantly higher overall gap formation at reduced residual loading (analysis of covariance, < .001) compared with both the double-CL loop and adjustable fixation techniques. The adjustable group showed the highest failure load and stiffness, at 305.7 N and 117.1 N/mm, respectively. The failure load of the knotted single-CL group was significantly reduced compared with all other groups ( < .001).
Adjustable single-CL cortical button fixation with intraoperative preconditioning optimized time-zero ACL tension and led to significantly improved stabilization and reduced gap formation, with the highest ultimate strength. Single-CL loop knot tying over the button and knotless anchor fixation resulted in time-zero gaps to achieve slight tension on the ACL and significantly higher gap formation at reduced load-bearing capability.
Although the clinical relevance of gap formation is uncertain, a biomechanical understanding of the stabilization potential of current ACL repair techniques is pertinent to the continued evolution of surgical approaches to enable better clinical outcomes.
最近,人们对前交叉韧带(ACL)的一期修复兴趣再度兴起,固定技术也在不断发展。然而,迄今为止,尚无生物力学研究比较固定与可调固定修复技术。
与固定技术相比,可调ACL修复在间隙形成和残余承重能力方面能提供更好的稳定性。
对照实验室研究。
使用猪模型测试了总共4种不同的ACL修复技术(每组n = 5),包括单环和双环皮质纽扣固定以及无结单缝线锚定固定。对于可调单环固定,进行了额外的预处理(0.5 Hz下10个循环)。对于固定技术,测量固定后的力和达到10 N初始预载时的致动器位移。在拉伸至破坏(50 mm/min)之前,以0.75 Hz进行从1至8 mm的递增循环(1 mm/500个循环),共4000个循环。分析每个测试块的最终残余峰值载荷、间隙形成以及极限强度。
与双环固定和可调固定技术相比,单环在纽扣上打结(均值±标准差,0.66±0.23 mm)和无结锚定固定(0.20±0.12 mm)导致显著的初始间隙(P <.001),并且在残余负荷降低时总体间隙形成显著更高(协方差分析,P <.001)。可调组显示出最高的破坏载荷和刚度,分别为305.7 N和117.1 N/mm。与所有其他组相比,打结单环组的破坏载荷显著降低(P <.001)。
术中预处理的可调单环皮质纽扣固定优化了ACL的初始张力,显著提高了稳定性并减少了间隙形成,具有最高的极限强度。单环在纽扣上打结和无结锚定固定导致初始间隙,使ACL上有轻微张力,并且在承重能力降低时间隙形成显著更高。
尽管间隙形成的临床意义尚不确定,但对当前ACL修复技术稳定潜力的生物力学理解对于手术方法的持续发展以实现更好的临床结果至关重要。