Lajeunesse Michael, Young Scott
Madigan Army Medical Center, Department of Emergency Medicine, Tacoma, Washington.
Clin Pract Cases Emerg Med. 2020 Jan 24;4(1):75-78. doi: 10.5811/cpcem.2019.11.44966. eCollection 2020 Feb.
Thyrotoxic hypokalemic periodic paralysis (THPP) is a condition that results in transient skeletal muscle paralysis secondary to intracellular potassium sequestration. Susceptible individuals often have an underlying channelopathy, which may be exacerbated by lifestyle factors or underlying medical comorbidities such as hyperthyroidism or diarrheal illness. Classically, THPP presents with paralysis of proximal extremity musculature. In this case, we present a rare case of unilateral THPP. Such a presentation is relevant to emergency physicians as it mimics a stroke or transient ischemic attack and should be considered on the differential for unilateral neurologic deficits.
甲状腺毒症性低钾性周期性麻痹(THPP)是一种由于细胞内钾离子隔离导致的短暂性骨骼肌麻痹疾病。易感个体通常存在潜在的离子通道病,生活方式因素或潜在的内科合并症(如甲状腺功能亢进或腹泻性疾病)可能会加重病情。典型的THPP表现为近端肢体肌肉麻痹。在此,我们报告一例罕见的单侧THPP病例。这种表现对于急诊医生来说具有重要意义,因为它酷似中风或短暂性脑缺血发作,在单侧神经功能缺损的鉴别诊断中应予以考虑。