Kuznetsova Julia, Sereda Yulia, Denisiuk Olga, Kravchenko Nataliia, Jayaraj Joshua, Smyrnov Pavlo, Mykhalchuk Tetiana, Zachariah Rony
Alliance for Public Health, Kyiv, Ukraine.
Independent Consultant, Maria Primachenko Blvd., 8-B, Apartment 52, Kyiv, Ukraine.
J Infect Dev Ctries. 2019 Jul 31;13(7.1):95S-102S. doi: 10.3855/jidc.11291.
Alliance for Public Health, the International Charitable Foundation, coordinates HIV prevention in Non-Governmental Organizations (NGO) working with people who inject drugs (PWID) in Ukraine. We aimed to describe the performance of the differential model of linking PWID to HIV care and treatment (Community Initiated Treatment Intervention - CITI).
A retrospective cohort study using routine program data was conducted among 8,927 PWID who were tested positive for the first time during January 2016 - June 2017. Study outcomes were enrollment into CITI and initiating antiretroviral treatment (ART). Factors associated with outcomes were estimated by logistic regressions with random effects.
Among the study participants, 54% enrolled into CITI and 23% initiated ART. CITI enrolment was associated with being married (adjusted odds ratio (AOR) = 1.17; 95%: 1.02-1.34); less than weekly compared to daily (AOR = 1.31; 95%: 1.13-1.52); less than 5 years of drug use compared to > 14 years (AOR = 1.73; 95%: 1.40-2.13), and having no criminal records (AOR = 1.30; 95%: 1.12-1.50). Factors of non-ART initiation were male gender (AOR = 1.33; 95%: 1.16-1.53); being single (AOR = 1.48; 95%: 1.21-1.82); drug use duration > 14 years compared to < 5 years (AOR = 1.38; 95%: 1.03-1.85), unemployment (AOR = 1.45; 95%: 1.15-1.83) and history of incarceration (AOR = 1.21; 95%: 1.003-1.45).
Mobilizing the NGO community and PWID to engage in outreach HIV testing activity and harm reduction for key populations has succeeded in opening the gateway to prevention, care and ART for thousands of PWID in Ukraine.
国际慈善基金会公共卫生联盟在乌克兰协调非政府组织(NGO)中针对注射吸毒者(PWID)的艾滋病毒预防工作。我们旨在描述将注射吸毒者与艾滋病毒护理和治疗相联系的差异模型(社区启动治疗干预 - CITI)的表现。
使用常规项目数据进行了一项回顾性队列研究,研究对象为2016年1月至2017年6月期间首次检测呈阳性的8927名注射吸毒者。研究结果是加入CITI和开始抗逆转录病毒治疗(ART)。通过具有随机效应的逻辑回归估计与结果相关的因素。
在研究参与者中,54%加入了CITI,23%开始接受ART治疗。加入CITI与已婚有关(调整后的优势比(AOR)=1.17;95%:1.02 - 1.34);与每天吸毒相比,每周吸毒少于一次(AOR = 1.31;95%:1.13 - 1.52);吸毒少于5年与吸毒超过14年相比(AOR = 1.73;95%:1.40 - 2.13),以及没有犯罪记录(AOR = 1.30;95%:1.12 - 1.50)。未开始接受ART治疗的因素包括男性(AOR = 1.33;95%:1.16 - 1.53);单身(AOR = 1.48;95%:1.21 - 1.82);吸毒持续时间超过14年与少于5年相比(AOR = 1.38;95%:1.03 - 1.85),失业(AOR = 1.45;95%:1.15 - 1.83)和有监禁史(AOR = 1.21;95%:1.003 - 1.45)。
动员非政府组织社区和注射吸毒者参与外展艾滋病毒检测活动及对关键人群的减少伤害工作,已成功为乌克兰数千名注射吸毒者打开了预防、护理和接受抗逆转录病毒治疗的大门。