Institute of Mathematical and Computer Sciences, University of Sao Paulo, Brazil.
Department of Physical Therapy, Federal University of Sao Carlos, Brazil.
Comput Methods Programs Biomed. 2020 Jul;191:105376. doi: 10.1016/j.cmpb.2020.105376. Epub 2020 Feb 7.
Bedridden patients presenting chronic skin ulcers often need to be examined at home. Healthcare professionals follow the evolution of the patients' condition by regularly taking pictures of the wounds, as different aspects of the wound can indicate the healing stages of the ulcer, including depth, location, and size. The manual measurement of the wounds' size is often inaccurate, time-consuming, and can also cause discomfort to the patient. In this work, we propose the Automatic Skin Ulcer Region Assessment ASURA framework to accurately segment the wound and automatically measure its size.
ASURA uses an encoder/decoder deep neural network to perform the segmentation, which detects the measurement ruler/tape present in the image and estimates its pixel density.
Experimental results show that ASURA outperforms the state-of-the-art methods by up to 16% regarding the Dice score, being able to correctly segment the wound with a Dice score higher than 90%. ASURA automatically estimates the pixel density of the images with a relative error of 5%. When using a semi-automatic approach, ASURA was able to estimate the area of the wound in square centimeters with a relative error of 14%.
The results show that ASURA is well-suited for the problem of segmenting and automatically measuring skin ulcers.
长期卧床的慢性皮肤溃疡患者通常需要在家中接受检查。医护人员通过定期拍摄伤口的照片来跟踪患者病情的变化,因为伤口的不同方面可以指示溃疡的愈合阶段,包括深度、位置和大小。手动测量伤口的大小通常不够准确,既耗时又可能给患者带来不适。在这项工作中,我们提出了自动皮肤溃疡区域评估(Automatic Skin Ulcer Region Assessment,ASURA)框架,以准确分割伤口并自动测量其大小。
ASURA 使用编码器/解码器深度神经网络进行分割,该网络检测图像中存在的测量标尺/胶带,并估计其像素密度。
实验结果表明,ASURA 在骰子分数方面的表现优于最先进的方法,最高可达 16%,能够以高于 90%的骰子分数正确分割伤口。ASURA 能够以 5%的相对误差自动估计图像的像素密度。当使用半自动方法时,ASURA 能够以 14%的相对误差估计平方厘米的伤口面积。
结果表明,ASURA 非常适合分割和自动测量皮肤溃疡的问题。