Oncology Department, The First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, Jiangsu, PR China.
Hepatobiliary Center, The First Affiliated Hospital, Nanjing Medical University, Jiangsu, PR China.
Future Oncol. 2020 Mar;16(7):293-306. doi: 10.2217/fon-2019-0552. Epub 2020 Feb 18.
Colorectal cancer is the third most common cancer in the world and its incidence is on the rise. Dietary intervention has emerged as an attractive strategy to curtail its occurrence and progression. Diet is known to influence the gut microbiome, as dietary factors and gut bacteria can act in concert to cause or protect from colorectal cancer. Several studies have presented evidence for such interactions and have pointed out the different ways by which the diet and gut microbiome can be altered to produce beneficial effects. This review article aims to summarize the interrelationship between diet, gut flora and colorectal cancer so that a better preventive approach can be applied.
结直肠癌是世界上第三大常见癌症，其发病率呈上升趋势。饮食干预已成为一种有吸引力的策略，可以减少其发生和发展。饮食被认为会影响肠道微生物群，因为饮食因素和肠道细菌可以协同作用导致或预防结直肠癌。有几项研究已经提供了这种相互作用的证据，并指出了可以改变饮食和肠道微生物群以产生有益效果的不同方式。本文综述了饮食、肠道菌群与结直肠癌之间的相互关系，以期提出更好的预防方法。
