GRASP55：一种多功能蛋白。
GRASP55: A Multifunctional Protein.
机构信息
Institute of Pathogenic Biology, Hengyang Medical College, University of South China, Hengyang, China.
Hengyang Medical College, University of South China, Hengyang, China.
出版信息
Curr Protein Pept Sci. 2020;21(6):544-552. doi: 10.2174/1389203721666200218105302.
GRASP55 was first found as Golgi cisternae stacking protein. Due to the crucial role of Golgi in vesicular trafficking and protein modification, GRASP55 was found to function in these two aspects. Further investigation revealed that GRASP55 also participates in the unconventional secretory pathway under stress. Moreover, GRASP55 is involved in autophagy initiation and autophagosome maturation, as well as cell activity.
GRASP55 最初被发现是作为高尔基潴泡堆叠蛋白。由于高尔基体在囊泡运输和蛋白质修饰中的关键作用，GRASP55 在这两个方面都发挥了作用。进一步的研究表明，GRASP55 还参与应激下的非经典分泌途径。此外，GRASP55 还参与自噬的起始和自噬体的成熟以及细胞活性。
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