Occurrence of bisphenol A and its alternatives in paired urine and indoor dust from Chinese university students: Implications for human exposure.

Bisphenol analogs (BPs), as the industrial chemicals, are widely used in consumer products. Limited information exists regarding human exposure to BPs in university students in China. In this study, we detected concentrations of seven BPs, namely bisphenol A (BPA), bisphenol AF (BPAF), bisphenol P (BPP), bisphenol AP (BPAP), bisphenol Z (BPZ), bisphenol S (BPS), and bisphenol F (BPF), in paired urine (n = 160) and indoor dust samples (n = 40) from university students in South China. High detection rates and levels (median) was found in BPA in paired urine (99%, 3.57 ng/mL) and indoor dust (80%, 2.98 μg/g) samples, followed by BPS (88%, 0.24 ng/mL; 78%, 0.22 μg/g). These findings suggest that BPA remains the major BPs used in consumer products. A positive relationship between urinary ∑BPs (sum of six BPs) concentration and indoor dust was observed (r = 0.444, p < 0.01), indicated that exposure to non-dietary BPs may also be significant to human exposure. The median EDI values (ng/kg bw/day) of ∑BPs in males (119.6) were relatively higher than (p < 0.05) those in females (84.6). By contrast, the median EDI of BPs (except for BPAF) in dust form female dormitories were slightly higher than that in dust from male dormitories. Notably, BPF was the most ingested from indoor dust (dormitory dust). This study is the first time to document the occurrence of BPs in paired urine and indoor dust in university students from China.