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普雷耶反射——豚鼠听力功能的简易评估方法。

The Preyer reflex--an easy estimate of hearing function in guinea pigs.

作者信息

Böhmer A

机构信息

ENT Department, University Hospital, Zürich, Switzerland.

出版信息

Acta Otolaryngol. 1988 Nov-Dec;106(5-6):368-72. doi: 10.3109/00016488809122259.

DOI:10.3109/00016488809122259
PMID:3207004
Abstract

Preyer reflex thresholds elicited monaurally by tone bursts from 0.25 to 8 kHz were determined in more than 150 guinea pig ears. Normal reflex thresholds were between 85 and 95 dB SPL in the low and middle frequencies, decreasing to 75 dB in the higher frequencies. The range of measurements at single frequencies usually did not exceed 10 dB. In unselected populations of adult guinea pigs, about half of the animals had increased reflex thresholds--at least unilaterally, in most cases due to middle ear infections. The Preyer reflex showed parallel threshold increase with compound action potential thresholds in conductive loss and recruitment in cochlear hearing loss. Normal Preyer reflex thresholds do not necessarily mean normal hearing, but increased thresholds do indicate hearing impairment. This technique is valuable in the selection and monitoring of animals for otologic experiments.

摘要

在150多只豚鼠耳朵上测定了由0.25至8千赫的短纯音单耳诱发的普赖尔反射阈值。在低频和中频,正常反射阈值在85至95分贝声压级之间,在高频则降至75分贝。单频测量范围通常不超过10分贝。在未经过挑选的成年豚鼠群体中,约一半动物的反射阈值升高——至少是单侧的,大多数情况下是由于中耳感染。在传导性听力损失时,普赖尔反射阈值与复合动作电位阈值平行升高,在耳蜗性听力损失时则与重振现象平行。正常的普赖尔反射阈值并不一定意味着听力正常,但阈值升高确实表明存在听力障碍。这项技术在选择和监测用于耳科学实验的动物方面很有价值。

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