Larsen H C, Albers F, Jansson B, Angelborg C, Veldman J
Department of Otolaryngology, Akademiska Sjukhuset, University of Uppsala, Sweden.
Acta Otolaryngol. 1988 Nov-Dec;106(5-6):404-8. doi: 10.3109/00016488809122263.
There is no animal model for Meniere's disease but by obliteration of the endolymphatic duct, endolymphatic hydrops may be achieved in several animal species. In order to measure the cochlear blood flow in ears with endolymphatic hydrops the endolymphatic duct was obliterated in 9 guinea pigs. The blood flow was measured with the microsphere method and the cochlear histology was studied. The regional and total blood flow was determined in the serially sectioned cochleas 2, 4 and 8 months after obliteration of the endolymphatic duct. No change in regional or total cochlear blood flow was observed in the hydropic ears.
梅尼埃病没有动物模型，但通过闭塞内淋巴管，在几种动物物种中可以实现内淋巴积水。为了测量有内淋巴积水耳朵的耳蜗血流量，对9只豚鼠进行了内淋巴管闭塞术。采用微球法测量血流量，并研究耳蜗组织学。在内淋巴管闭塞后2、4和8个月，对连续切片的耳蜗进行局部和总血流量测定。在积水耳朵中未观察到局部或总耳蜗血流量的变化。
