脂肪移植科学
The Science of Fat Grafting.
作者信息
Shih Linden, Davis Matthew J, Winocour Sebastian J
机构信息
Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
出版信息
Semin Plast Surg. 2020 Feb;34(1):5-10. doi: 10.1055/s-0039-3402073. Epub 2020 Feb 15.
Abstract
Autologous fat grafting has become a popular and well-established technique used by plastic surgeons in a variety of aesthetic and reconstructive procedures. An understanding of the basic science principles underlying fat grafting is crucial to explaining its extensive utility for soft tissue rejuvenation, volume augmentation, and body contouring-and the unpredictable fat resorption rates after grafting that pose a significant challenge for plastic surgeons. While the scientific principles of fat grafting can theoretically be exploited to optimize fat grafting techniques and increase fat tissue survival, a consensus has yet been established as to the best practices for this procedure. This review discusses the biology of adipose tissue and the scientific principles behind its behavior and survival in autologous fat grafting.
摘要
自体脂肪移植已成为整形外科医生在各种美容和重建手术中常用的一种流行且成熟的技术。了解脂肪移植背后的基础科学原理对于解释其在软组织年轻化、容积增大和身体塑形方面的广泛应用至关重要，同时也有助于理解移植后不可预测的脂肪吸收率，这对整形外科医生构成了重大挑战。虽然从理论上讲，可以利用脂肪移植的科学原理来优化脂肪移植技术并提高脂肪组织的存活率，但对于该手术的最佳操作方法尚未达成共识。本综述讨论了脂肪组织的生物学特性以及自体脂肪移植中其行为和存活背后的科学原理。
相似文献
1
The Science of Fat Grafting.脂肪移植科学
Semin Plast Surg. 2020 Feb;34(1):5-10. doi: 10.1055/s-0039-3402073. Epub 2020 Feb 15.
2
The science of autologous fat grafting: views on current and future approaches to neoadipogenesis.自体脂肪移植科学：关于当前及未来新脂肪形成方法的观点
Aesthet Surg J. 2008 May-Jun;28(3):313-21; quiz 322-4. doi: 10.1016/j.asj.2008.02.004.
3
Principles and Applications of Fat Grafting in Plastic Surgery.整形手术中脂肪移植的原理与应用
Semin Plast Surg. 2019 Aug;33(3):147-154. doi: 10.1055/s-0039-1693438. Epub 2019 Aug 2.
4
Fat grafting to the breast and adipose-derived stem cells: recent scientific consensus and controversy.脂肪移植到乳房和脂肪来源的干细胞：最新的科学共识和争议。
Aesthet Surg J. 2010 May-Jun;30(3):381-7. doi: 10.1177/1090820X10373063.
5
Fat Grafting for Facial Filling and Regeneration.用于面部填充和再生的脂肪移植
Clin Plast Surg. 2015 Jul;42(3):289-300, vii. doi: 10.1016/j.cps.2015.04.001.
6
Review: Proposed Methods to Improve the Survival of Adipose Tissue in Autologous Fat Grafting.综述：提高自体脂肪移植中脂肪组织存活率的建议方法
Plast Reconstr Surg Glob Open. 2018 Aug 3;6(8):e1870. doi: 10.1097/GOX.0000000000001870. eCollection 2018 Aug.
7
Future Perspectives of Fat Grafting.脂肪移植的未来展望
Clin Plast Surg. 2015 Jul;42(3):389-94, ix-x. doi: 10.1016/j.cps.2015.03.007. Epub 2015 Apr 18.
8
Fat grafting in aesthetics.脂肪移植在美学中的应用。
Clin Dermatol. 2022 Jan-Feb;40(1):35-44. doi: 10.1016/j.clindermatol.2021.08.010. Epub 2021 Aug 8.
9
Autologous fat grafting: Harvesting techniques.自体脂肪移植：采集技术。
Ann Med Surg (Lond). 2018 Nov 13;36:212-218. doi: 10.1016/j.amsu.2018.11.005. eCollection 2018 Dec.
10
An Overview of Principles and New Techniques for Facial Fat Grafting.面部脂肪移植的原则和新技术概述。
Clin Plast Surg. 2020 Jan;47(1):7-17. doi: 10.1016/j.cps.2019.08.001. Epub 2019 Oct 21.
引用本文的文献
1
Shaping the Silhouette: A Comprehensive Review of Surgical Body Contouring Techniques for the Torso and Limbs.塑造身形：躯干和四肢手术塑形技术的全面综述
Cureus. 2025 Jul 25;17(7):e88737. doi: 10.7759/cureus.88737. eCollection 2025 Jul.
2
Optimizing Aesthetic Facial Surgery Outcomes Following Minimally Invasive Treatments: Guidelines for Perioperative Management.微创治疗后优化面部美容手术效果：围手术期管理指南
Aesthet Surg J Open Forum. 2025 Jul 4;7:ojaf087. doi: 10.1093/asjof/ojaf087. eCollection 2025.
3
Current Modalities in Soft-Tissue Reconstruction and Vascularized Adipose Engineering.软组织重建与血管化脂肪组织工程的当前模式
Biomolecules. 2025 May 28;15(6):780. doi: 10.3390/biom15060780.
4
Giant Cyst of Dermis-Fat Graft in a Child with MRSA-Case Report.一名患有耐甲氧西林金黄色葡萄球菌（MRSA）儿童的真皮脂肪移植巨大囊肿——病例报告
Children (Basel). 2025 Apr 2;12(4):457. doi: 10.3390/children12040457.
5
PRP pre-treatment of the implantation zone improves the survival rate of fat autograft.植入区的富血小板血浆预处理可提高自体脂肪移植的存活率。
Front Bioeng Biotechnol. 2025 Apr 11;13:1545419. doi: 10.3389/fbioe.2025.1545419. eCollection 2025.
6
The Influence of Sedimentation on the Composition of the Lipoaspirate and the Effects on Further Mechanical Processing.脂肪抽吸物中沉淀对其成分的影响及对后续机械处理的作用
Cells. 2025 Apr 16;14(8):601. doi: 10.3390/cells14080601.
7
Novel breast reconstruction technique using ex vivo mononuclear (RE-01) cells and adipose-derived mesenchymal stem cells.使用体外单核（RE-01）细胞和脂肪来源间充质干细胞的新型乳房重建技术。
Regen Ther. 2025 Mar 29;29:271-281. doi: 10.1016/j.reth.2025.03.018. eCollection 2025 Jun.
8
Helium Plasma Effect on Breast Stromal-Enriched Lipograft: A Case Report.氦等离子体对富含乳腺基质的脂肪移植的影响：一例报告
Aesthet Surg J Open Forum. 2024 Dec 9;6:ojae087. doi: 10.1093/asjof/ojae087. eCollection 2024.
9
Early activation of macrophage-2 with IL-4 in stromal vascular fraction increases VEGF levels and adipocyte count and maintains volume of fat graft in Wistar rats ().在Wistar大鼠的基质血管成分中，用白细胞介素-4早期激活巨噬细胞-2可增加血管内皮生长因子水平和脂肪细胞数量，并维持脂肪移植体的体积（）。
Narra J. 2024 Dec;4(3):e1080. doi: 10.52225/narra.v4i3.1080. Epub 2024 Oct 11.
10
Enrichment of Fat Graft with Association of ASC and Nanofat in an Animal Model.在动物模型中通过脂肪干细胞与纳米脂肪联合来富集脂肪移植物
Aesthetic Plast Surg. 2025 Feb;49(3):908-916. doi: 10.1007/s00266-024-04322-5. Epub 2024 Oct 14.
本文引用的文献
1
Principles and Applications of Fat Grafting in Plastic Surgery.整形手术中脂肪移植的原理与应用
Semin Plast Surg. 2019 Aug;33(3):147-154. doi: 10.1055/s-0039-1693438. Epub 2019 Aug 2.
2
The Preparation of the Recipient Site in Fat Grafting: A Comprehensive Review of the Preclinical Evidence.脂肪移植受区准备：临床前证据的综合回顾。
Plast Reconstr Surg. 2019 Apr;143(4):1099-1107. doi: 10.1097/PRS.0000000000005403.
3
Autologous fat grafting: Latest insights.自体脂肪移植：最新见解。
Ann Med Surg (Lond). 2018 Oct 16;37:47-53. doi: 10.1016/j.amsu.2018.10.016. eCollection 2019 Jan.
4
Fat Grafting Can Induce Browning of White Adipose Tissue.脂肪移植可诱导白色脂肪组织褐变。
Plast Reconstr Surg Glob Open. 2018 Jun 19;6(6):e1804. doi: 10.1097/GOX.0000000000001804. eCollection 2018 Jun.
5
The science behind autologous fat grafting.自体脂肪移植背后的科学原理。
Ann Med Surg (Lond). 2017 Nov 10;24:65-73. doi: 10.1016/j.amsu.2017.11.001. eCollection 2017 Dec.
6
Effect, Feasibility, and Clinical Relevance of Cell Enrichment in Large Volume Fat Grafting: A Systematic Review.大容量脂肪移植中细胞富集的效果、可行性及临床相关性：一项系统评价
Aesthet Surg J. 2017 Jul 1;37(suppl_3):S46-S58. doi: 10.1093/asj/sjx008.
7
Autologous fat transfer for breast surgery.用于乳房手术的自体脂肪移植。
Br J Hosp Med (Lond). 2017 Aug 2;78(8):448-452. doi: 10.12968/hmed.2017.78.8.448.
8
Current Clinical Applications of Fat Grafting.脂肪移植的当前临床应用
Plast Reconstr Surg. 2017 Sep;140(3):466e-486e. doi: 10.1097/PRS.0000000000003648.
9
Autologous Fat Grafting: The Science Behind the Surgery.自体脂肪移植：手术背后的科学
Aesthet Surg J. 2016 Apr;36(4):488-96. doi: 10.1093/asj/sjw004.
10
Mechanisms of Fat Graft Survival.脂肪移植存活的机制。
Ann Plast Surg. 2016 Feb;77 Suppl 1:S84-6. doi: 10.1097/SAP.0000000000000730.
Zotero 插件